L127-0818 Screening compound: 4-CHLORO-N1-[2-(2-METHYLPIPERIDINO)ETHYL]-N1-[2-(PIPERAZINOSULFONYL)ETHYL]-1-BENZENESULFONAMIDE

L127-0818 Screening compound: 4-CHLORO-N1-[2-(2-METHYLPIPERIDINO)ETHYL]-N1-[2-(PIPERAZINOSULFONYL)ETHYL]-1-BENZENESULFONAMIDE
L127-0818 Screening compound: 4-CHLORO-N1-[2-(2-METHYLPIPERIDINO)ETHYL]-N1-[2-(PIPERAZINOSULFONYL)ETHYL]-1-BENZENESULFONAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound L127-0818
4-CHLORO-N1-[2-(2-METHYLPIPERIDINO)ETHYL]-N1-[2-(PIPERAZINOSULFONYL)ETHYL]-1-BENZENESULFONAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L127-0818

Molecular Formula

C20H33ClN4O4S2 (C20 H33 ClN4 O4 S2)

Compound Name

4-CHLORO-N1-[2-(2-METHYLPIPERIDINO)ETHYL]-N1-[2-(PIPERAZINOSULFONYL)ETHYL]-1-BENZENESULFONAMIDE

IUPAC name

n/a

SMILES

CC1N(CCN(CCS(N2CCNCC2)(=O)=O)S(c(cc2)ccc2Cl)(=O)=O)CCCC1

InChI

InChI=1S/C20H33ClN4O4S2/c1-18-4-2-3-11-23(18)14-15-25(31(28,29)20-7-5-19(21)6-8-20)16-17-30(26,27)24-12-9-22-10-13-24/h5-8,18,22H,2-4,9-17H2,1H3/t18-/m0/s1

InChI Key

OYRAWTYZJPIGBR-SFHVURJKSA-N

MDL Number (MFCD)

MFCD15119128

Chemical and Physical Properties

Saltdata

CF3COOH

Molecular Weight

493.09

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.550

Distribution Coefficient, logD

1.149

Water Solubility, LogSw

-2.73

Polar Surface Area

78.570

Acid Dissociation Constant (pKa)

22.14

Base Dissociation Constant (pKb)

7.58

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

70.00

L127-0818 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L127-0818 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L127-0818?
Check Price and Availability of L127-0818, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L127-0818 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L127-0818
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L127-0818
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L127-0818 available by request