L150-0053 Screening compound: 2,8-dimethyl-4-oxo-N~3~-(3,4,5-trimethoxyphenyl)-4H-pyrimido[2,1-b][1,3]benzothiazole-3-sulfonamide

L150-0053 Screening compound: 2,8-dimethyl-4-oxo-N~3~-(3,4,5-trimethoxyphenyl)-4H-pyrimido[2,1-b][1,3]benzothiazole-3-sulfonamide
L150-0053 Screening compound: 2,8-dimethyl-4-oxo-N~3~-(3,4,5-trimethoxyphenyl)-4H-pyrimido[2,1-b][1,3]benzothiazole-3-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L150-0053
2,8-dimethyl-4-oxo-N~3~-(3,4,5-trimethoxyphenyl)-4H-pyrimido[2,1-b][1,3]benzothiazole-3-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L150-0053

Molecular Formula

C21H21N3O6S2 (C21 H21 N3 O6 S2)

Compound Name

2,8-dimethyl-4-oxo-N~3~-(3,4,5-trimethoxyphenyl)-4H-pyrimido[2,1-b][1,3]benzothiazole-3-sulfonamide

IUPAC name

511-dimethyl-13-oxo-N-(345-trimethoxyphenyl)-8-thia-110-diazatricyclo[7.4.0.0^{27}]trideca-246911-pentaene-12-sulfonamide

SMILES

Cc(cc1)cc(SC2=NC(C)=C3S(Nc(cc4OC)cc(OC)c4OC)(=O)=O)c1N2C3=O

InChI

InChI=1S/C21H21N3O6S2/c1-11-6-7-14-17(8-11)31-21-22-12(2)19(20(25)24(14)21)32(26,27)23-13-9-15(28-3)18(30-5)16(10-13)29-4/h6-10,23H,1-5H3

InChI Key

GSTXIMRSYVIWDB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15119165

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

475.55

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.338

Distribution Coefficient, logD

-0.947

Water Solubility, LogSw

-2.97

Polar Surface Area

88.311

Acid Dissociation Constant (pKa)

4.12

Base Dissociation Constant (pKb)

-5.27

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

L150-0053 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L150-0053 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L150-0053?
Check Price and Availability of L150-0053, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L150-0053 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L150-0053
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L150-0053
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L150-0053 available by request