L150-0080 Screening compound: 3-(4-methylphenyl)-N-[2-oxo-4-(propylamino)-2H-chromen-3-yl]-2,1-benzoxazole-5-carboxamide

L150-0080 Screening compound: 3-(4-methylphenyl)-N-[2-oxo-4-(propylamino)-2H-chromen-3-yl]-2,1-benzoxazole-5-carboxamide
L150-0080 Screening compound: 3-(4-methylphenyl)-N-[2-oxo-4-(propylamino)-2H-chromen-3-yl]-2,1-benzoxazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L150-0080
3-(4-methylphenyl)-N-[2-oxo-4-(propylamino)-2H-chromen-3-yl]-2,1-benzoxazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L150-0080

Molecular Formula

C27H23N3O4 (C27 H23 N3 O4)

Compound Name

3-(4-methylphenyl)-N-[2-oxo-4-(propylamino)-2H-chromen-3-yl]-2,1-benzoxazole-5-carboxamide

IUPAC name

3-(4-methylphenyl)-N-[2-oxo-4-(propylamino)-2H-chromen-3-yl]-21-benzoxazole-5-carboxamide

SMILES

CCCNC(c(cccc1)c1OC1=O)=C1NC(c1cc2c(-c3ccc(C)cc3)onc2cc1)=O

InChI

InChI=1S/C27H23N3O4/c1-3-14-28-23-19-6-4-5-7-22(19)33-27(32)24(23)29-26(31)18-12-13-21-20(15-18)25(34-30-21)17-10-8-16(2)9-11-17/h4-13,15,28H,3,14H2,1-2H3,(H,29,31)

InChI Key

AXOJXRZVYAMLHL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27234331

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

453.5

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.054

Distribution Coefficient, logD

4.621

Water Solubility, LogSw

-4.64

Polar Surface Area

76.480

Acid Dissociation Constant (pKa)

7.17

Base Dissociation Constant (pKb)

3.31

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.80

L150-0080 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • Others
  • GPCR
Mechanism of action:
  • Epigenetic
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L150-0080 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L150-0080?
Check Price and Availability of L150-0080, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L150-0080 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L150-0080
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L150-0080
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L150-0080 available by request