L150-0320 Screening compound: N-[2-({3-bromo-1-[(4-methylphenyl)methyl]-1H-1,2,4-triazol-5-yl}sulfanyl)phenyl]cyclohexanecarboxamide

L150-0320 Screening compound: N-[2-({3-bromo-1-[(4-methylphenyl)methyl]-1H-1,2,4-triazol-5-yl}sulfanyl)phenyl]cyclohexanecarboxamide
L150-0320 Screening compound: N-[2-({3-bromo-1-[(4-methylphenyl)methyl]-1H-1,2,4-triazol-5-yl}sulfanyl)phenyl]cyclohexanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L150-0320
N-[2-({3-bromo-1-[(4-methylphenyl)methyl]-1H-1,2,4-triazol-5-yl}sulfanyl)phenyl]cyclohexanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L150-0320

Molecular Formula

C23H25BrN4OS (C23 H25 BrN4 OS)

Compound Name

N-[2-({3-bromo-1-[(4-methylphenyl)methyl]-1H-1,2,4-triazol-5-yl}sulfanyl)phenyl]cyclohexanecarboxamide

IUPAC name

N-[2-({3-bromo-1-[(4-methylphenyl)methyl]-1H-124-triazol-5-yl}sulfanyl)phenyl]cyclohexanecarboxamide

SMILES

Cc1ccc(Cn(c(Sc(cccc2)c2NC(C2CCCCC2)=O)n2)nc2Br)cc1

InChI

InChI=1S/C23H25BrN4OS/c1-16-11-13-17(14-12-16)15-28-23(26-22(24)27-28)30-20-10-6-5-9-19(20)25-21(29)18-7-3-2-4-8-18/h5-6,9-14,18H,2-4,7-8,15H2,1H3,(H,25,29)

InChI Key

URMSFVDXYWQFCF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15119332

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

485.45

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.809

Distribution Coefficient, logD

5.809

Water Solubility, LogSw

-5.32

Polar Surface Area

47.621

Acid Dissociation Constant (pKa)

13.58

Base Dissociation Constant (pKb)

-0.80

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.80

L150-0320 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L150-0320 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L150-0320?
Check Price and Availability of L150-0320, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L150-0320 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L150-0320
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L150-0320
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L150-0320 available by request