L150-0515 Screening compound: N-(4-fluorophenyl)-N'-(2-hydroxy-4-methyl-6-quinolyl)urea

L150-0515 Screening compound: N-(4-fluorophenyl)-N'-(2-hydroxy-4-methyl-6-quinolyl)urea
L150-0515 Screening compound: N-(4-fluorophenyl)-N'-(2-hydroxy-4-methyl-6-quinolyl)urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L150-0515
N-(4-fluorophenyl)-N'-(2-hydroxy-4-methyl-6-quinolyl)urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L150-0515

Molecular Formula

C17H14FN3O2 (C17 H14 FN3 O2)

Compound Name

N-(4-fluorophenyl)-N'-(2-hydroxy-4-methyl-6-quinolyl)urea

IUPAC name

n/a

SMILES

Cc1c(cc(cc2)NC(Nc(cc3)ccc3F)=O)c2nc(O)c1

InChI

InChI=1S/C17H14FN3O2/c1-10-8-16(22)21-15-7-6-13(9-14(10)15)20-17(23)19-12-4-2-11(18)3-5-12/h2-9H,1H3,(H,21,22)(H2,19,20,23)

InChI Key

NZIJCFMIQQDHSI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15119431

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

311.32

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.072

Distribution Coefficient, logD

4.021

Water Solubility, LogSw

-4.08

Polar Surface Area

58.131

Acid Dissociation Constant (pKa)

8.30

Base Dissociation Constant (pKb)

1.50

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.90

L150-0515 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Glucocorticoid receptors Library (4806 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L150-0515 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L150-0515?
Check Price and Availability of L150-0515, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L150-0515 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L150-0515
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L150-0515
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L150-0515 available by request