L153-0098 Screening compound: N-[2-(1H-indol-3-yl)ethyl]-2-[1-(3-methyl-1-phenyl-1H-pyrazole-4-carbonyl)piperidin-4-yl]acetamide

L153-0098 Screening compound: N-[2-(1H-indol-3-yl)ethyl]-2-[1-(3-methyl-1-phenyl-1H-pyrazole-4-carbonyl)piperidin-4-yl]acetamide
L153-0098 Screening compound: N-[2-(1H-indol-3-yl)ethyl]-2-[1-(3-methyl-1-phenyl-1H-pyrazole-4-carbonyl)piperidin-4-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L153-0098
N-[2-(1H-indol-3-yl)ethyl]-2-[1-(3-methyl-1-phenyl-1H-pyrazole-4-carbonyl)piperidin-4-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L153-0098

Molecular Formula

C28H31N5O2 (C28 H31 N5 O2)

Compound Name

N-[2-(1H-indol-3-yl)ethyl]-2-[1-(3-methyl-1-phenyl-1H-pyrazole-4-carbonyl)piperidin-4-yl]acetamide

IUPAC name

N-[2-(1H-indol-3-yl)ethyl]-2-[1-(3-methyl-1-phenyl-1H-pyrazole-4-carbonyl)piperidin-4-yl]acetamide

SMILES

Cc(c(C(N1CCC(CC(NCCc2c[nH]c3c2cccc3)=O)CC1)=O)c1)nn1-c1ccccc1

InChI

InChI=1S/C28H31N5O2/c1-20-25(19-33(31-20)23-7-3-2-4-8-23)28(35)32-15-12-21(13-16-32)17-27(34)29-14-11-22-18-30-26-10-6-5-9-24(22)26/h2-10,18-19,21,30H,11-17H2,1H3,(H,29,34)

InChI Key

GCOKNRSWIVCBBW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27234816

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

469.59

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.230

Distribution Coefficient, logD

3.230

Water Solubility, LogSw

-3.42

Polar Surface Area

65.510

Acid Dissociation Constant (pKa)

14.12

Base Dissociation Constant (pKb)

1.25

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.10

L153-0098 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

GPCR Targeted Library (31838 compounds)

Indole Derivatives (10091 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Cyclic compounds
  • Mimetics
  • Mimetics
Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with L153-0098 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L153-0098?
Check Price and Availability of L153-0098, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L153-0098 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L153-0098
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L153-0098
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L153-0098 available by request