L153-0449 Screening compound: 2-[1-(1,3-diphenyl-1H-pyrazole-4-carbonyl)piperidin-4-yl]-N-[(pyridin-3-yl)methyl]propanamide

L153-0449 Screening compound: 2-[1-(1,3-diphenyl-1H-pyrazole-4-carbonyl)piperidin-4-yl]-N-[(pyridin-3-yl)methyl]propanamide
L153-0449 Screening compound: 2-[1-(1,3-diphenyl-1H-pyrazole-4-carbonyl)piperidin-4-yl]-N-[(pyridin-3-yl)methyl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L153-0449
2-[1-(1,3-diphenyl-1H-pyrazole-4-carbonyl)piperidin-4-yl]-N-[(pyridin-3-yl)methyl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L153-0449

Molecular Formula

C30H31N5O2 (C30 H31 N5 O2)

Compound Name

2-[1-(1,3-diphenyl-1H-pyrazole-4-carbonyl)piperidin-4-yl]-N-[(pyridin-3-yl)methyl]propanamide

IUPAC name

2-[1-(13-diphenyl-1H-pyrazole-4-carbonyl)piperidin-4-yl]-N-[(pyridin-3-yl)methyl]propanamide

SMILES

CC(C(CC1)CCN1C(c1cn(-c2ccccc2)nc1-c1ccccc1)=O)C(NCc1cnccc1)=O

InChI

InChI=1S/C30H31N5O2/c1-22(29(36)32-20-23-9-8-16-31-19-23)24-14-17-34(18-15-24)30(37)27-21-35(26-12-6-3-7-13-26)33-28(27)25-10-4-2-5-11-25/h2-13,16,19,21-22,24H,14-15,17-18,20H2,1H3,(H,32,36)/t22-/m0/s1

InChI Key

MYYLZMCQAOZDHK-QFIPXVFZSA-N

MDL Number (MFCD)

MFCD15119776

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

493.61

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.116

Distribution Coefficient, logD

3.114

Water Solubility, LogSw

-3.14

Polar Surface Area

65.451

Acid Dissociation Constant (pKa)

13.36

Base Dissociation Constant (pKb)

5.15

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

26.70

L153-0449 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L153-0449 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L153-0449?
Check Price and Availability of L153-0449, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L153-0449 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L153-0449
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L153-0449
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L153-0449 available by request