L154-0036 Screening compound: N-(2-chlorobenzyl)-1-(4-methyl-2-pyrimidinyl)-3-piperidinecarboxamide

L154-0036 Screening compound: N-(2-chlorobenzyl)-1-(4-methyl-2-pyrimidinyl)-3-piperidinecarboxamide
L154-0036 Screening compound: N-(2-chlorobenzyl)-1-(4-methyl-2-pyrimidinyl)-3-piperidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L154-0036
N-(2-chlorobenzyl)-1-(4-methyl-2-pyrimidinyl)-3-piperidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L154-0036

Molecular Formula

C18H21ClN4O (C18 H21 ClN4 O)

Compound Name

N-(2-chlorobenzyl)-1-(4-methyl-2-pyrimidinyl)-3-piperidinecarboxamide

IUPAC name

N-[(2-chlorophenyl)methyl]-1-(4-methylpyrimidin-2-yl)piperidine-3-carboxamide

SMILES

Cc1ccnc(N(CCC2)CC2C(NCc(cccc2)c2Cl)=O)n1

InChI

InChI=1S/C18H21ClN4O/c1-13-8-9-20-18(22-13)23-10-4-6-15(12-23)17(24)21-11-14-5-2-3-7-16(14)19/h2-3,5,7-9,15H,4,6,10-12H2,1H3,(H,21,24)

InChI Key

RPOJSTRBBVKOCL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04204300

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

344.84

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.941

Distribution Coefficient, logD

2.941

Water Solubility, LogSw

-3.28

Polar Surface Area

45.774

Acid Dissociation Constant (pKa)

12.49

Base Dissociation Constant (pKb)

3.59

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

38.89

L154-0036 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L154-0036 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L154-0036?
Check Price and Availability of L154-0036, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L154-0036 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L154-0036
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L154-0036
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L154-0036 available by request