L154-0263 Screening compound: N-({1-[(4-chlorophenyl)methyl]piperidin-4-yl}methyl)-1-(4-methylpyrimidin-2-yl)piperidine-3-carboxamide

L154-0263 Screening compound: N-({1-[(4-chlorophenyl)methyl]piperidin-4-yl}methyl)-1-(4-methylpyrimidin-2-yl)piperidine-3-carboxamide
L154-0263 Screening compound: N-({1-[(4-chlorophenyl)methyl]piperidin-4-yl}methyl)-1-(4-methylpyrimidin-2-yl)piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L154-0263
N-({1-[(4-chlorophenyl)methyl]piperidin-4-yl}methyl)-1-(4-methylpyrimidin-2-yl)piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L154-0263

Molecular Formula

C24H32ClN5O (C24 H32 ClN5 O)

Compound Name

N-({1-[(4-chlorophenyl)methyl]piperidin-4-yl}methyl)-1-(4-methylpyrimidin-2-yl)piperidine-3-carboxamide

IUPAC name

N-({1-[(4-chlorophenyl)methyl]piperidin-4-yl}methyl)-1-(4-methylpyrimidin-2-yl)piperidine-3-carboxamide

SMILES

Cc1ccnc(N(CCC2)CC2C(NCC2CCN(Cc(cc3)ccc3Cl)CC2)=O)n1

InChI

InChI=1S/C24H32ClN5O/c1-18-8-11-26-24(28-18)30-12-2-3-21(17-30)23(31)27-15-19-9-13-29(14-10-19)16-20-4-6-22(25)7-5-20/h4-8,11,19,21H,2-3,9-10,12-17H2,1H3,(H,27,31)/t21-/m0/s1

InChI Key

DSDXGIIUDHCWPP-NRFANRHFSA-N

MDL Number (MFCD)

MFCD27234892

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

442

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.702

Distribution Coefficient, logD

2.066

Water Solubility, LogSw

-4.03

Polar Surface Area

49.507

Acid Dissociation Constant (pKa)

14.08

Base Dissociation Constant (pKb)

9.03

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

54.20

L154-0263 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Therapeutical Diversity Annotated Library (7563 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Nervous system
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds
Agro:
  • Agro

References: we are preparing a list of scientific research reports with L154-0263 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L154-0263?
Check Price and Availability of L154-0263, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L154-0263 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L154-0263
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L154-0263
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L154-0263 available by request