L154-0309 Screening compound: N-(2-{[(furan-2-yl)methyl](2-phenylethyl)amino}ethyl)-1-(4-methylpyrimidin-2-yl)piperidine-3-carboxamide

L154-0309 Screening compound: N-(2-{[(furan-2-yl)methyl](2-phenylethyl)amino}ethyl)-1-(4-methylpyrimidin-2-yl)piperidine-3-carboxamide
L154-0309 Screening compound: N-(2-{[(furan-2-yl)methyl](2-phenylethyl)amino}ethyl)-1-(4-methylpyrimidin-2-yl)piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L154-0309
N-(2-{[(furan-2-yl)methyl](2-phenylethyl)amino}ethyl)-1-(4-methylpyrimidin-2-yl)piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L154-0309

Molecular Formula

C26H33N5O2 (C26 H33 N5 O2)

Compound Name

N-(2-{[(furan-2-yl)methyl](2-phenylethyl)amino}ethyl)-1-(4-methylpyrimidin-2-yl)piperidine-3-carboxamide

IUPAC name

N-(2-{[(furan-2-yl)methyl](2-phenylethyl)amino}ethyl)-1-(4-methylpyrimidin-2-yl)piperidine-3-carboxamide

SMILES

Cc1ccnc(N(CCC2)CC2C(NCCN(CCc2ccccc2)Cc2ccco2)=O)n1

InChI

InChI=1S/C26H33N5O2/c1-21-11-13-28-26(29-21)31-15-5-9-23(19-31)25(32)27-14-17-30(20-24-10-6-18-33-24)16-12-22-7-3-2-4-8-22/h2-4,6-8,10-11,13,18,23H,5,9,12,14-17,19-20H2,1H3,(H,27,32)/t23-/m0/s1

InChI Key

AKLAQLLZNMZAPA-QHCPKHFHSA-N

MDL Number (MFCD)

MFCD27234914

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

447.58

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.422

Distribution Coefficient, logD

3.317

Water Solubility, LogSw

-3.33

Polar Surface Area

57.033

Acid Dissociation Constant (pKa)

13.28

Base Dissociation Constant (pKb)

6.83

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

42.30

L154-0309 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

GPCR Targeted Library (31838 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L154-0309 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L154-0309?
Check Price and Availability of L154-0309, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L154-0309 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L154-0309
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L154-0309
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L154-0309 available by request