L154-0575 Screening compound: N-({1-[(3-chlorophenyl)methyl]piperidin-4-yl}methyl)-1-(4-methylpyrimidin-2-yl)piperidine-3-carboxamide

L154-0575 Screening compound: N-({1-[(3-chlorophenyl)methyl]piperidin-4-yl}methyl)-1-(4-methylpyrimidin-2-yl)piperidine-3-carboxamide
L154-0575 Screening compound: N-({1-[(3-chlorophenyl)methyl]piperidin-4-yl}methyl)-1-(4-methylpyrimidin-2-yl)piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L154-0575
N-({1-[(3-chlorophenyl)methyl]piperidin-4-yl}methyl)-1-(4-methylpyrimidin-2-yl)piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L154-0575

Molecular Formula

C24H32ClN5O (C24 H32 ClN5 O)

Compound Name

N-({1-[(3-chlorophenyl)methyl]piperidin-4-yl}methyl)-1-(4-methylpyrimidin-2-yl)piperidine-3-carboxamide

IUPAC name

N-({1-[(3-chlorophenyl)methyl]piperidin-4-yl}methyl)-1-(4-methylpyrimidin-2-yl)piperidine-3-carboxamide

SMILES

Cc1ccnc(N(CCC2)CC2C(NCC2CCN(Cc3cccc(Cl)c3)CC2)=O)n1

InChI

InChI=1S/C24H32ClN5O/c1-18-7-10-26-24(28-18)30-11-3-5-21(17-30)23(31)27-15-19-8-12-29(13-9-19)16-20-4-2-6-22(25)14-20/h2,4,6-7,10,14,19,21H,3,5,8-9,11-13,15-17H2,1H3,(H,27,31)/t21-/m0/s1

InChI Key

ZOAVGBHEOVNVHS-NRFANRHFSA-N

MDL Number (MFCD)

MFCD27234931

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

442

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.763

Distribution Coefficient, logD

1.946

Water Solubility, LogSw

-3.99

Polar Surface Area

49.507

Acid Dissociation Constant (pKa)

14.08

Base Dissociation Constant (pKb)

9.21

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

54.20

L154-0575 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Anti-Inflammatory Library (24602 compounds)

CNS Targets (44014 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Cyclic compounds
Therapeutical areas:
  • Immune system
  • Nervous system
  • Nervous system
  • Nervous system
  • Cardiovascular
Targets:
  • GPCR
  • Ion Channels
  • Ion Channels
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with L154-0575 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L154-0575?
Check Price and Availability of L154-0575, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L154-0575 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L154-0575
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L154-0575
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L154-0575 available by request