L162-0167 Screening compound: 1-[4-(4-chlorophenyl)piperazin-1-yl]-N-(propan-2-yl)isoquinoline-7-carboxamide

L162-0167 Screening compound: 1-[4-(4-chlorophenyl)piperazin-1-yl]-N-(propan-2-yl)isoquinoline-7-carboxamide
L162-0167 Screening compound: 1-[4-(4-chlorophenyl)piperazin-1-yl]-N-(propan-2-yl)isoquinoline-7-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L162-0167
1-[4-(4-chlorophenyl)piperazin-1-yl]-N-(propan-2-yl)isoquinoline-7-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L162-0167

Molecular Formula

C23H25ClN4O (C23 H25 ClN4 O)

Compound Name

1-[4-(4-chlorophenyl)piperazin-1-yl]-N-(propan-2-yl)isoquinoline-7-carboxamide

IUPAC name

1-[4-(4-chlorophenyl)piperazin-1-yl]-N-(propan-2-yl)isoquinoline-7-carboxamide

SMILES

CC(C)NC(c1ccc(ccnc2N(CC3)CCN3c(cc3)ccc3Cl)c2c1)=O

InChI

InChI=1S/C23H25ClN4O/c1-16(2)26-23(29)18-4-3-17-9-10-25-22(21(17)15-18)28-13-11-27(12-14-28)20-7-5-19(24)6-8-20/h3-10,15-16H,11-14H2,1-2H3,(H,26,29)

InChI Key

KNXREAFZUCYBCA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27235186

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

408.93

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.800

Distribution Coefficient, logD

4.787

Water Solubility, LogSw

-4.87

Polar Surface Area

39.320

Acid Dissociation Constant (pKa)

13.83

Base Dissociation Constant (pKb)

5.90

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.40

L162-0167 in Drug Discovery

Included in Screening Libraries

Anti-infective Library (19449 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with L162-0167 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L162-0167?
Check Price and Availability of L162-0167, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L162-0167 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L162-0167
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L162-0167
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L162-0167 available by request