L162-0323 Screening compound: 1-[4-(4-fluorophenyl)piperazin-1-yl]-N-[2-(1H-indol-3-yl)ethyl]isoquinoline-7-carboxamide

L162-0323 Screening compound: 1-[4-(4-fluorophenyl)piperazin-1-yl]-N-[2-(1H-indol-3-yl)ethyl]isoquinoline-7-carboxamide
L162-0323 Screening compound: 1-[4-(4-fluorophenyl)piperazin-1-yl]-N-[2-(1H-indol-3-yl)ethyl]isoquinoline-7-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L162-0323
1-[4-(4-fluorophenyl)piperazin-1-yl]-N-[2-(1H-indol-3-yl)ethyl]isoquinoline-7-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L162-0323

Molecular Formula

C30H28FN5O (C30 H28 FN5 O)

Compound Name

1-[4-(4-fluorophenyl)piperazin-1-yl]-N-[2-(1H-indol-3-yl)ethyl]isoquinoline-7-carboxamide

IUPAC name

1-[4-(4-fluorophenyl)piperazin-1-yl]-N-[2-(1H-indol-3-yl)ethyl]isoquinoline-7-carboxamide

SMILES

O=C(c1ccc(ccnc2N(CC3)CCN3c(cc3)ccc3F)c2c1)NCCc1c[nH]c2c1cccc2

InChI

InChI=1S/C30H28FN5O/c31-24-7-9-25(10-8-24)35-15-17-36(18-16-35)29-27-19-22(6-5-21(27)11-13-32-29)30(37)33-14-12-23-20-34-28-4-2-1-3-26(23)28/h1-11,13,19-20,34H,12,14-18H2,(H,33,37)

InChI Key

PKVTUNFADYRIDM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27235248

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

493.58

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.365

Distribution Coefficient, logD

5.352

Water Solubility, LogSw

-6.03

Polar Surface Area

49.786

Acid Dissociation Constant (pKa)

12.81

Base Dissociation Constant (pKb)

5.90

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

L162-0323 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

CORONAVIRUS Library (20774 compounds)

Indole Derivatives (10091 compounds)

PLpro Library (6343 compounds)

Akt-Targeted Library (14764 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Structure:
  • Cyclic compounds
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L162-0323 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L162-0323?
Check Price and Availability of L162-0323, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L162-0323 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L162-0323
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L162-0323
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L162-0323 available by request