L162-0459 Screening compound: 1-[4-(2-fluorophenyl)piperazin-1-yl]-7-(morpholine-4-carbonyl)isoquinoline

L162-0459 Screening compound: 1-[4-(2-fluorophenyl)piperazin-1-yl]-7-(morpholine-4-carbonyl)isoquinoline
L162-0459 Screening compound: 1-[4-(2-fluorophenyl)piperazin-1-yl]-7-(morpholine-4-carbonyl)isoquinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound L162-0459
1-[4-(2-fluorophenyl)piperazin-1-yl]-7-(morpholine-4-carbonyl)isoquinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L162-0459

Molecular Formula

C24H25FN4O2 (C24 H25 FN4 O2)

Compound Name

1-[4-(2-fluorophenyl)piperazin-1-yl]-7-(morpholine-4-carbonyl)isoquinoline

IUPAC name

1-[4-(2-fluorophenyl)piperazin-1-yl]-7-(morpholine-4-carbonyl)isoquinoline

SMILES

O=C(c1ccc(ccnc2N(CC3)CCN3c(cccc3)c3F)c2c1)N1CCOCC1

InChI

InChI=1S/C24H25FN4O2/c25-21-3-1-2-4-22(21)27-9-11-28(12-10-27)23-20-17-19(6-5-18(20)7-8-26-23)24(30)29-13-15-31-16-14-29/h1-8,17H,9-16H2

InChI Key

ZHKPAYDWVCKMIY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27235297

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

420.49

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.281

Distribution Coefficient, logD

3.267

Water Solubility, LogSw

-3.49

Polar Surface Area

39.916

Acid Dissociation Constant (pKa)

23.24

Base Dissociation Constant (pKb)

5.90

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

L162-0459 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Targeted Diversity Library (40567 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L162-0459 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L162-0459?
Check Price and Availability of L162-0459, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L162-0459 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L162-0459
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L162-0459
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L162-0459 available by request