L207-0383 Screening compound: ethyl 5-(cyclohexylamino)-6-(4-hydroxyphenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxylate

L207-0383 Screening compound: ethyl 5-(cyclohexylamino)-6-(4-hydroxyphenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxylate
L207-0383 Screening compound: ethyl 5-(cyclohexylamino)-6-(4-hydroxyphenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound L207-0383
ethyl 5-(cyclohexylamino)-6-(4-hydroxyphenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L207-0383

Molecular Formula

C21H25N3O3S (C21 H25 N3 O3 S)

Compound Name

ethyl 5-(cyclohexylamino)-6-(4-hydroxyphenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxylate

IUPAC name

ethyl 5-(cyclohexylamino)-6-(4-hydroxyphenyl)-3-methylimidazo[21-b][13]thiazole-2-carboxylate

SMILES

CCOC(c(s1)c(C)n2c1nc(-c(cc1)ccc1O)c2NC1CCCCC1)=O

InChI

InChI=1S/C21H25N3O3S/c1-3-27-20(26)18-13(2)24-19(22-15-7-5-4-6-8-15)17(23-21(24)28-18)14-9-11-16(25)12-10-14/h9-12,15,22,25H,3-8H2,1-2H3

InChI Key

HIPCDSYVYKPQDO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27236010

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

399.51

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.724

Distribution Coefficient, logD

4.716

Water Solubility, LogSw

-4.21

Polar Surface Area

57.742

Acid Dissociation Constant (pKa)

9.31

Base Dissociation Constant (pKb)

5.14

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.90

L207-0383 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Hsp90-Targeted Library (11355 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L207-0383 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L207-0383?
Check Price and Availability of L207-0383, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L207-0383 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L207-0383
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L207-0383
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L207-0383 available by request