L207-0418 Screening compound: ethyl 6-[3-(benzyloxy)phenyl]-5-(cyclopentylamino)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxylate

L207-0418 Screening compound: ethyl 6-[3-(benzyloxy)phenyl]-5-(cyclopentylamino)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxylate
L207-0418 Screening compound: ethyl 6-[3-(benzyloxy)phenyl]-5-(cyclopentylamino)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound L207-0418
ethyl 6-[3-(benzyloxy)phenyl]-5-(cyclopentylamino)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L207-0418

Molecular Formula

C27H29N3O3S (C27 H29 N3 O3 S)

Compound Name

ethyl 6-[3-(benzyloxy)phenyl]-5-(cyclopentylamino)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxylate

IUPAC name

ethyl 6-[3-(benzyloxy)phenyl]-5-(cyclopentylamino)-3-methylimidazo[21-b][13]thiazole-2-carboxylate

SMILES

CCOC(c(s1)c(C)n2c1nc(-c1cc(OCc3ccccc3)ccc1)c2NC1CCCC1)=O

InChI

InChI=1S/C27H29N3O3S/c1-3-32-26(31)24-18(2)30-25(28-21-13-7-8-14-21)23(29-27(30)34-24)20-12-9-15-22(16-20)33-17-19-10-5-4-6-11-19/h4-6,9-12,15-16,21,28H,3,7-8,13-14,17H2,1-2H3

InChI Key

VGFGKTXJWPPYBB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27236025

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

475.61

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

6.470

Distribution Coefficient, logD

6.355

Water Solubility, LogSw

-5.62

Polar Surface Area

47.718

Acid Dissociation Constant (pKa)

21.24

Base Dissociation Constant (pKb)

6.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

L207-0418 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L207-0418 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L207-0418?
Check Price and Availability of L207-0418, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L207-0418 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L207-0418
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L207-0418
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L207-0418 available by request