L218-0264 Screening compound: N~1~-(2,5-difluorophenyl)-2-[2-(4-fluorophenyl)-4-oxopyrimido[1,2-a][1,3]benzimidazol-10(4H)-yl]acetamide
Chemical Structure Depiction of ChemDiv screening compound L218-0264
N~1~-(2,5-difluorophenyl)-2-[2-(4-fluorophenyl)-4-oxopyrimido[1,2-a][1,3]benzimidazol-10(4H)-yl]acetamide
Available from 1 mg
Formats:
- Glass Vials (4ml Glass Vials VWR #97047-678)
- 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)
Shiptime: 1 week worldwide delivery in most cases
Compound Identifiers
ChemDiv Compound ID
L218-0264
Molecular Formula
C24H15F3N4O2 (C24 H15 F3 N4 O2)
Compound Name
N~1~-(2,5-difluorophenyl)-2-[2-(4-fluorophenyl)-4-oxopyrimido[1,2-a][1,3]benzimidazol-10(4H)-yl]acetamide
IUPAC name
N-(25-difluorophenyl)-2-[11-(4-fluorophenyl)-13-oxo-1810-triazatricyclo[7.4.0.0^{27}]trideca-246911-pentaen-8-yl]acetamide
SMILES
O=C(CN(c(cccc1)c1N12)C2=NC(c(cc2)ccc2F)=CC1=O)Nc(cc(cc1)F)c1F
InChI Key
MDL Number (MFCD)
Chemical and Physical Properties
Saltdata
n/a
Molecular Weight
448.4
Hydrogen Bond Acceptors Count
5.00
Hydrogen Bond Donors Count
1.00
Rotatable Bond Count
5.00
Number of Nitrogen and Oxygen Atoms
6
Partition Coefficient, logP
3.869
Distribution Coefficient, logD
3.860
Water Solubility, LogSw
-4.24
Polar Surface Area
50.536
Acid Dissociation Constant (pKa)
9.11
Base Dissociation Constant (pKb)
0.78
Number of Chiral Centers
0.00
Percent sp3 carbon bonding
4.20
L218-0264 in Drug Discovery
Included in Screening Libraries
Angiogenesis library (14822 compounds)
Anticancer Library (62698 compounds)
DGK Inhibitors Library (10558 compounds)
Serine Proteases Inhibitors Library (32732 compounds)
Included in 1.7M Stock Database
- Cancer
- Cancer
- Cancer
- Digestive system
- Hemic and lymphatic
- Skin
- Metabolic
- Immune system
- Infections
- Cancer
- Musculoskeletal
- Digestive system
- Respiratory tract
- Male
- Female
- Cardiovascular
- Skin
- Metabolic
- Immune system
- Kinases
- Proteases
References: we are preparing a list of scientific research reports with L218-0264 chemical compound. It will be published here after verification.
Frequently Asked Questions
Check Price and Availability of L218-0264, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
Available from 1 mg in Glass Vials or 96-tube racks.
ChemDiv sends parcels with Express services (UPS, WC).
- 1–2 days for small orders
- 2–4 weeks for large selections
- 0.5–50 mg of dry powder sample in single glass vials, custom vials
- DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)