L218-0369 Screening compound: N~1~-(1,3-benzodioxol-5-yl)-2-[2-(4-methoxyphenyl)-4-oxopyrimido[1,2-a][1,3]benzimidazol-10(4H)-yl]acetamide
Chemical Structure Depiction of ChemDiv screening compound L218-0369
N~1~-(1,3-benzodioxol-5-yl)-2-[2-(4-methoxyphenyl)-4-oxopyrimido[1,2-a][1,3]benzimidazol-10(4H)-yl]acetamide
Available from 1 mg
Formats:
- Glass Vials (4ml Glass Vials VWR #97047-678)
- 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)
Shiptime: 1 week worldwide delivery in most cases
Compound Identifiers
ChemDiv Compound ID
L218-0369
Molecular Formula
C26H20N4O5 (C26 H20 N4 O5)
Compound Name
N~1~-(1,3-benzodioxol-5-yl)-2-[2-(4-methoxyphenyl)-4-oxopyrimido[1,2-a][1,3]benzimidazol-10(4H)-yl]acetamide
IUPAC name
N-(2H-13-benzodioxol-5-yl)-2-[11-(4-methoxyphenyl)-13-oxo-1810-triazatricyclo[7.4.0.0^{27}]trideca-246911-pentaen-8-yl]acetamide
SMILES
COc(cc1)ccc1C(N=C1N2c(cccc3)c3N1CC(Nc(cc1)cc3c1OCO3)=O)=CC2=O
InChI Key
MDL Number (MFCD)
Chemical and Physical Properties
Saltdata
n/a
Molecular Weight
468.47
Hydrogen Bond Acceptors Count
8.00
Hydrogen Bond Donors Count
1.00
Rotatable Bond Count
6.00
Number of Nitrogen and Oxygen Atoms
9
Partition Coefficient, logP
3.488
Distribution Coefficient, logD
3.488
Water Solubility, LogSw
-3.77
Polar Surface Area
75.893
Acid Dissociation Constant (pKa)
11.57
Base Dissociation Constant (pKb)
1.49
Number of Chiral Centers
0.00
Percent sp3 carbon bonding
11.50
L218-0369 in Drug Discovery
Included in Screening Libraries
Anticancer Library (62698 compounds)
DGK Inhibitors Library (10558 compounds)
Serine Proteases Inhibitors Library (32732 compounds)
SmartTM Library (51161 compounds)
Adenosine Receptors Targeted Library (19896 compounds)
Included in 1.7M Stock Database
- Cancer
- Cancer
- Digestive system
- Hemic and lymphatic
- Skin
- Metabolic
- Immune system
- Infections
- Cancer
- Musculoskeletal
- Digestive system
- Respiratory tract
- Male
- Female
- Cardiovascular
- Skin
- Metabolic
- Immune system
- Cancer
- Digestive system
- Respiratory tract
- Nervous system
- Eye
- Cardiovascular
- Kinases
- Proteases
- GPCR
- Receptor's ligands
References: we are preparing a list of scientific research reports with L218-0369 chemical compound. It will be published here after verification.
Frequently Asked Questions
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Available from 1 mg in Glass Vials or 96-tube racks.
ChemDiv sends parcels with Express services (UPS, WC).
- 1–2 days for small orders
- 2–4 weeks for large selections
- 0.5–50 mg of dry powder sample in single glass vials, custom vials
- DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)