L220-0399 Screening compound: N-{[1-(4-methylbenzoyl)-2,3-dihydro-1H-indol-6-yl]methyl}methanesulfonamide

L220-0399 Screening compound: N-{[1-(4-methylbenzoyl)-2,3-dihydro-1H-indol-6-yl]methyl}methanesulfonamide
L220-0399 Screening compound: N-{[1-(4-methylbenzoyl)-2,3-dihydro-1H-indol-6-yl]methyl}methanesulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L220-0399
N-{[1-(4-methylbenzoyl)-2,3-dihydro-1H-indol-6-yl]methyl}methanesulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L220-0399

Molecular Formula

C18H20N2O3S (C18 H20 N2 O3 S)

Compound Name

N-{[1-(4-methylbenzoyl)-2,3-dihydro-1H-indol-6-yl]methyl}methanesulfonamide

IUPAC name

N-{[1-(4-methylbenzoyl)-23-dihydro-1H-indol-6-yl]methyl}methanesulfonamide

SMILES

Cc(cc1)ccc1C(N(CC1)c2c1ccc(CNS(C)(=O)=O)c2)=O

InChI

InChI=1S/C18H20N2O3S/c1-13-3-6-16(7-4-13)18(21)20-10-9-15-8-5-14(11-17(15)20)12-19-24(2,22)23/h3-8,11,19H,9-10,12H2,1-2H3

InChI Key

JAJJWUNECCJLCN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27236263

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

344.43

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.517

Distribution Coefficient, logD

2.517

Water Solubility, LogSw

-2.87

Polar Surface Area

58.893

Acid Dissociation Constant (pKa)

10.75

Base Dissociation Constant (pKb)

-2.25

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

L220-0399 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Arginase Targeted Library (2009 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Epigenetics Focused Set (26518 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Musculoskeletal
  • Male
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Mechanism of action:
  • Epigenetic
  • Receptor's ligands
  • Epigenetic
Targets:
  • Others
  • GPCR

References: we are preparing a list of scientific research reports with L220-0399 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L220-0399?
Check Price and Availability of L220-0399, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L220-0399 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L220-0399
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L220-0399
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L220-0399 available by request