L222-0153 Screening compound: 4-methoxyphenyl [4-(4-methylphenyl)-4H-pyrrolo[1,2-a][1,4]benzodiazepin-5(6H)-yl] sulfone

L222-0153 Screening compound: 4-methoxyphenyl [4-(4-methylphenyl)-4H-pyrrolo[1,2-a][1,4]benzodiazepin-5(6H)-yl] sulfone
L222-0153 Screening compound: 4-methoxyphenyl [4-(4-methylphenyl)-4H-pyrrolo[1,2-a][1,4]benzodiazepin-5(6H)-yl] sulfone alternative view

Chemical Structure Depiction of ChemDiv screening compound L222-0153
4-methoxyphenyl [4-(4-methylphenyl)-4H-pyrrolo[1,2-a][1,4]benzodiazepin-5(6H)-yl] sulfone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L222-0153

Molecular Formula

C26H24N2O3S (C26 H24 N2 O3 S)

Compound Name

4-methoxyphenyl [4-(4-methylphenyl)-4H-pyrrolo[1,2-a][1,4]benzodiazepin-5(6H)-yl] sulfone

IUPAC name

8-(4-methoxybenzenesulfonyl)-7-(4-methylphenyl)-28-diazatricyclo[8.4.0.0^{26}]tetradeca-1(10)351113-pentaene

SMILES

Cc1ccc(C(c2cccn2-c2c(C3)cccc2)N3S(c(cc2)ccc2OC)(=O)=O)cc1

InChI

InChI=1S/C26H24N2O3S/c1-19-9-11-20(12-10-19)26-25-8-5-17-27(25)24-7-4-3-6-21(24)18-28(26)32(29,30)23-15-13-22(31-2)14-16-23/h3-17,26H,18H2,1-2H3/t26-/m1/s1

InChI Key

SKWCAUVDDKZGQH-AREMUKBSSA-N

MDL Number (MFCD)

MFCD15120431

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

444.55

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.971

Distribution Coefficient, logD

5.971

Water Solubility, LogSw

-5.72

Polar Surface Area

41.134

Acid Dissociation Constant (pKa)

23.53

Base Dissociation Constant (pKb)

-4.80

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

15.40

L222-0153 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Epigenetics Focused Set (26518 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L222-0153 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L222-0153?
Check Price and Availability of L222-0153, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L222-0153 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L222-0153
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L222-0153
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L222-0153 available by request