L227-0002 Screening compound: N-(4-acetylphenyl)-1-[5-methyl-2-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-7-yl]piperidine-4-carboxamide

L227-0002 Screening compound: N-(4-acetylphenyl)-1-[5-methyl-2-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-7-yl]piperidine-4-carboxamide
L227-0002 Screening compound: N-(4-acetylphenyl)-1-[5-methyl-2-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-7-yl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L227-0002
N-(4-acetylphenyl)-1-[5-methyl-2-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-7-yl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L227-0002

Molecular Formula

C28H29N5O2 (C28 H29 N5 O2)

Compound Name

N-(4-acetylphenyl)-1-[5-methyl-2-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-7-yl]piperidine-4-carboxamide

IUPAC name

N-(4-acetylphenyl)-1-[5-methyl-2-(4-methylphenyl)pyrazolo[15-a]pyrimidin-7-yl]piperidine-4-carboxamide

SMILES

CC(c(cc1)ccc1NC(C(CC1)CCN1c1cc(C)nc2cc(-c3ccc(C)cc3)nn12)=O)=O

InChI

InChI=1S/C28H29N5O2/c1-18-4-6-22(7-5-18)25-17-26-29-19(2)16-27(33(26)31-25)32-14-12-23(13-15-32)28(35)30-24-10-8-21(9-11-24)20(3)34/h4-11,16-17,23H,12-15H2,1-3H3,(H,30,35)

InChI Key

WZEDRUCLOVIWCI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15120472

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

467.57

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.708

Distribution Coefficient, logD

2.553

Water Solubility, LogSw

-4.29

Polar Surface Area

58.652

Acid Dissociation Constant (pKa)

9.98

Base Dissociation Constant (pKb)

9.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

L227-0002 in Drug Discovery

Included in Screening Libraries

GABA Library (7115 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Eye
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
  • Ion Channels
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L227-0002 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L227-0002?
Check Price and Availability of L227-0002, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L227-0002 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L227-0002
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L227-0002
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L227-0002 available by request