L227-0031 Screening compound: N-(4-ethylphenyl)-1-[5-methyl-2-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-7-yl]piperidine-4-carboxamide

L227-0031 Screening compound: N-(4-ethylphenyl)-1-[5-methyl-2-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-7-yl]piperidine-4-carboxamide
L227-0031 Screening compound: N-(4-ethylphenyl)-1-[5-methyl-2-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-7-yl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L227-0031
N-(4-ethylphenyl)-1-[5-methyl-2-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-7-yl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L227-0031

Molecular Formula

C28H31N5O (C28 H31 N5 O)

Compound Name

N-(4-ethylphenyl)-1-[5-methyl-2-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-7-yl]piperidine-4-carboxamide

IUPAC name

N-(4-ethylphenyl)-1-[5-methyl-2-(4-methylphenyl)pyrazolo[15-a]pyrimidin-7-yl]piperidine-4-carboxamide

SMILES

CCc(cc1)ccc1NC(C(CC1)CCN1c1cc(C)nc2cc(-c3ccc(C)cc3)nn12)=O

InChI

InChI=1S/C28H31N5O/c1-4-21-7-11-24(12-8-21)30-28(34)23-13-15-32(16-14-23)27-17-20(3)29-26-18-25(31-33(26)27)22-9-5-19(2)6-10-22/h5-12,17-18,23H,4,13-16H2,1-3H3,(H,30,34)

InChI Key

RGZABJXVXSXGMO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15120485

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

453.59

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

6.096

Distribution Coefficient, logD

3.942

Water Solubility, LogSw

-5.36

Polar Surface Area

44.825

Acid Dissociation Constant (pKa)

11.95

Base Dissociation Constant (pKb)

9.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.10

L227-0031 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

GABA Library (7115 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Eye
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L227-0031 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L227-0031?
Check Price and Availability of L227-0031, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L227-0031 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L227-0031
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L227-0031
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L227-0031 available by request