L227-0200 Screening compound: 1-[2-(4-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]-N-(propan-2-yl)piperidine-4-carboxamide

L227-0200 Screening compound: 1-[2-(4-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]-N-(propan-2-yl)piperidine-4-carboxamide
L227-0200 Screening compound: 1-[2-(4-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]-N-(propan-2-yl)piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L227-0200
1-[2-(4-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]-N-(propan-2-yl)piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L227-0200

Molecular Formula

C22H26ClN5O (C22 H26 ClN5 O)

Compound Name

1-[2-(4-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]-N-(propan-2-yl)piperidine-4-carboxamide

IUPAC name

1-[2-(4-chlorophenyl)-5-methylpyrazolo[15-a]pyrimidin-7-yl]-N-(propan-2-yl)piperidine-4-carboxamide

SMILES

CC(C)NC(C(CC1)CCN1c1cc(C)nc2cc(-c(cc3)ccc3Cl)nn12)=O

InChI

InChI=1S/C22H26ClN5O/c1-14(2)24-22(29)17-8-10-27(11-9-17)21-12-15(3)25-20-13-19(26-28(20)21)16-4-6-18(23)7-5-16/h4-7,12-14,17H,8-11H2,1-3H3,(H,24,29)

InChI Key

OADQPMWVUXYSTL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15120530

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

411.93

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.380

Distribution Coefficient, logD

2.225

Water Solubility, LogSw

-4.52

Polar Surface Area

45.393

Acid Dissociation Constant (pKa)

14.90

Base Dissociation Constant (pKb)

9.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.90

L227-0200 in Drug Discovery

Included in Screening Libraries

GABA Library (7115 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Eye
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L227-0200 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L227-0200?
Check Price and Availability of L227-0200, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L227-0200 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L227-0200
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L227-0200
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L227-0200 available by request