L227-0382 Screening compound: N-{[4-(dimethylamino)phenyl]methyl}-1-[2-(4-methoxyphenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]piperidine-4-carboxamide

L227-0382 Screening compound: N-{[4-(dimethylamino)phenyl]methyl}-1-[2-(4-methoxyphenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]piperidine-4-carboxamide
L227-0382 Screening compound: N-{[4-(dimethylamino)phenyl]methyl}-1-[2-(4-methoxyphenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L227-0382
N-{[4-(dimethylamino)phenyl]methyl}-1-[2-(4-methoxyphenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L227-0382

Molecular Formula

C29H34N6O2 (C29 H34 N6 O2)

Compound Name

N-{[4-(dimethylamino)phenyl]methyl}-1-[2-(4-methoxyphenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]piperidine-4-carboxamide

IUPAC name

N-{[4-(dimethylamino)phenyl]methyl}-1-[2-(4-methoxyphenyl)-5-methylpyrazolo[15-a]pyrimidin-7-yl]piperidine-4-carboxamide

SMILES

Cc1nc2cc(-c(cc3)ccc3OC)nn2c(N(CC2)CCC2C(NCc(cc2)ccc2N(C)C)=O)c1

InChI

InChI=1S/C29H34N6O2/c1-20-17-28(35-27(31-20)18-26(32-35)22-7-11-25(37-4)12-8-22)34-15-13-23(14-16-34)29(36)30-19-21-5-9-24(10-6-21)33(2)3/h5-12,17-18,23H,13-16,19H2,1-4H3,(H,30,36)

InChI Key

YBRPUXGMXZZNGK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27236497

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

498.63

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.503

Distribution Coefficient, logD

2.349

Water Solubility, LogSw

-4.24

Polar Surface Area

56.496

Acid Dissociation Constant (pKa)

13.43

Base Dissociation Constant (pKb)

9.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.50

L227-0382 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CORONAVIRUS Library (20774 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

PLpro Library (6343 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with L227-0382 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L227-0382?
Check Price and Availability of L227-0382, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L227-0382 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L227-0382
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L227-0382
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L227-0382 available by request