L227-1230 Screening compound: 1-[2-(3,5-dimethylphenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]-N-{[4-(methylsulfanyl)phenyl]methyl}piperidine-4-carboxamide

L227-1230 Screening compound: 1-[2-(3,5-dimethylphenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]-N-{[4-(methylsulfanyl)phenyl]methyl}piperidine-4-carboxamide
L227-1230 Screening compound: 1-[2-(3,5-dimethylphenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]-N-{[4-(methylsulfanyl)phenyl]methyl}piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L227-1230
1-[2-(3,5-dimethylphenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]-N-{[4-(methylsulfanyl)phenyl]methyl}piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L227-1230

Molecular Formula

C29H33N5OS (C29 H33 N5 OS)

Compound Name

1-[2-(3,5-dimethylphenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]-N-{[4-(methylsulfanyl)phenyl]methyl}piperidine-4-carboxamide

IUPAC name

1-[2-(35-dimethylphenyl)-5-methylpyrazolo[15-a]pyrimidin-7-yl]-N-{[4-(methylsulfanyl)phenyl]methyl}piperidine-4-carboxamide

SMILES

Cc1cc(-c2nn3c(N(CC4)CCC4C(NCc(cc4)ccc4SC)=O)cc(C)nc3c2)cc(C)c1

InChI

InChI=1S/C29H33N5OS/c1-19-13-20(2)15-24(14-19)26-17-27-31-21(3)16-28(34(27)32-26)33-11-9-23(10-12-33)29(35)30-18-22-5-7-25(36-4)8-6-22/h5-8,13-17,23H,9-12,18H2,1-4H3,(H,30,35)

InChI Key

KGMJQHHPGZAGPV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15120648

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

499.68

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.679

Distribution Coefficient, logD

3.525

Water Solubility, LogSw

-5.40

Polar Surface Area

46.147

Acid Dissociation Constant (pKa)

12.56

Base Dissociation Constant (pKb)

9.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.50

L227-1230 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Antibacterial Compounds Library (13827 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Immune system
  • animal

References: we are preparing a list of scientific research reports with L227-1230 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L227-1230?
Check Price and Availability of L227-1230, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L227-1230 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L227-1230
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L227-1230
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L227-1230 available by request