L228-0859 Screening compound: 1-{[5-(2-cyclobutyl-1,3-oxazol-5-yl)thiophen-2-yl]sulfonyl}-4-phenylpiperazine

L228-0859 Screening compound: 1-{[5-(2-cyclobutyl-1,3-oxazol-5-yl)thiophen-2-yl]sulfonyl}-4-phenylpiperazine
L228-0859 Screening compound: 1-{[5-(2-cyclobutyl-1,3-oxazol-5-yl)thiophen-2-yl]sulfonyl}-4-phenylpiperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound L228-0859
1-{[5-(2-cyclobutyl-1,3-oxazol-5-yl)thiophen-2-yl]sulfonyl}-4-phenylpiperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L228-0859

Molecular Formula

C21H23N3O3S2 (C21 H23 N3 O3 S2)

Compound Name

1-{[5-(2-cyclobutyl-1,3-oxazol-5-yl)thiophen-2-yl]sulfonyl}-4-phenylpiperazine

IUPAC name

1-{[5-(2-cyclobutyl-13-oxazol-5-yl)thiophen-2-yl]sulfonyl}-4-phenylpiperazine

SMILES

O=S(c1ccc(-c2cnc(C3CCC3)o2)s1)(N(CC1)CCN1c1ccccc1)=O

InChI

InChI=1S/C21H23N3O3S2/c25-29(26,24-13-11-23(12-14-24)17-7-2-1-3-8-17)20-10-9-19(28-20)18-15-22-21(27-18)16-5-4-6-16/h1-3,7-10,15-16H,4-6,11-14H2

InChI Key

HYVUPHHSECJUJN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27236863

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

429.56

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.164

Distribution Coefficient, logD

4.163

Water Solubility, LogSw

-4.03

Polar Surface Area

54.203

Acid Dissociation Constant (pKa)

26.96

Base Dissociation Constant (pKb)

3.98

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.10

L228-0859 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L228-0859 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L228-0859?
Check Price and Availability of L228-0859, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L228-0859 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L228-0859
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L228-0859
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L228-0859 available by request