L228-1340 Screening compound: 1-{[5-(2-cyclopentyl-1,3-oxazol-5-yl)thiophen-2-yl]sulfonyl}-4-(furan-2-carbonyl)piperazine

L228-1340 Screening compound: 1-{[5-(2-cyclopentyl-1,3-oxazol-5-yl)thiophen-2-yl]sulfonyl}-4-(furan-2-carbonyl)piperazine
L228-1340 Screening compound: 1-{[5-(2-cyclopentyl-1,3-oxazol-5-yl)thiophen-2-yl]sulfonyl}-4-(furan-2-carbonyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound L228-1340
1-{[5-(2-cyclopentyl-1,3-oxazol-5-yl)thiophen-2-yl]sulfonyl}-4-(furan-2-carbonyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L228-1340

Molecular Formula

C21H23N3O5S2 (C21 H23 N3 O5 S2)

Compound Name

1-{[5-(2-cyclopentyl-1,3-oxazol-5-yl)thiophen-2-yl]sulfonyl}-4-(furan-2-carbonyl)piperazine

IUPAC name

1-{[5-(2-cyclopentyl-13-oxazol-5-yl)thiophen-2-yl]sulfonyl}-4-(furan-2-carbonyl)piperazine

SMILES

O=C(c1ccco1)N(CC1)CCN1S(c1ccc(-c2cnc(C3CCCC3)o2)s1)(=O)=O

InChI

InChI=1S/C21H23N3O5S2/c25-21(16-6-3-13-28-16)23-9-11-24(12-10-23)31(26,27)19-8-7-18(30-19)17-14-22-20(29-17)15-4-1-2-5-15/h3,6-8,13-15H,1-2,4-5,9-12H2

InChI Key

RWMZBAGDMZGJCB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27237025

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

461.56

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.645

Distribution Coefficient, logD

3.644

Water Solubility, LogSw

-3.61

Polar Surface Area

76.012

Acid Dissociation Constant (pKa)

26.22

Base Dissociation Constant (pKb)

4.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.90

L228-1340 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with L228-1340 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L228-1340?
Check Price and Availability of L228-1340, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L228-1340 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L228-1340
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L228-1340
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L228-1340 available by request