L228-1388 Screening compound: 4-{[5-(2-cyclopentyl-1,3-oxazol-5-yl)thiophen-2-yl]sulfonyl}morpholine

L228-1388 Screening compound: 4-{[5-(2-cyclopentyl-1,3-oxazol-5-yl)thiophen-2-yl]sulfonyl}morpholine
L228-1388 Screening compound: 4-{[5-(2-cyclopentyl-1,3-oxazol-5-yl)thiophen-2-yl]sulfonyl}morpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound L228-1388
4-{[5-(2-cyclopentyl-1,3-oxazol-5-yl)thiophen-2-yl]sulfonyl}morpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L228-1388

Molecular Formula

C16H20N2O4S2 (C16 H20 N2 O4 S2)

Compound Name

4-{[5-(2-cyclopentyl-1,3-oxazol-5-yl)thiophen-2-yl]sulfonyl}morpholine

IUPAC name

4-{[5-(2-cyclopentyl-13-oxazol-5-yl)thiophen-2-yl]sulfonyl}morpholine

SMILES

O=S(c1ccc(-c2cnc(C3CCCC3)o2)s1)(N1CCOCC1)=O

InChI

InChI=1S/C16H20N2O4S2/c19-24(20,18-7-9-21-10-8-18)15-6-5-14(23-15)13-11-17-16(22-13)12-3-1-2-4-12/h5-6,11-12H,1-4,7-10H2

InChI Key

IQAUMXRUABTEQI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27237040

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

368.48

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.361

Distribution Coefficient, logD

3.360

Water Solubility, LogSw

-3.17

Polar Surface Area

58.886

Acid Dissociation Constant (pKa)

26.22

Base Dissociation Constant (pKb)

4.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

56.30

L228-1388 in Drug Discovery

Included in Screening Libraries

Antiparasite Library (23996 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Agro:
  • Agro
  • Agro
Targets:
  • GPCR
  • Others
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with L228-1388 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L228-1388?
Check Price and Availability of L228-1388, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L228-1388 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L228-1388
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L228-1388
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L228-1388 available by request