L233-1703 Screening compound: 1-({5-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-2-methylthiophen-3-yl}sulfonyl)-4-(pyridin-2-yl)piperazine

L233-1703 Screening compound: 1-({5-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-2-methylthiophen-3-yl}sulfonyl)-4-(pyridin-2-yl)piperazine
L233-1703 Screening compound: 1-({5-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-2-methylthiophen-3-yl}sulfonyl)-4-(pyridin-2-yl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound L233-1703
1-({5-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-2-methylthiophen-3-yl}sulfonyl)-4-(pyridin-2-yl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L233-1703

Molecular Formula

C22H20FN5O3S2 (C22 H20 FN5 O3 S2)

Compound Name

1-({5-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-2-methylthiophen-3-yl}sulfonyl)-4-(pyridin-2-yl)piperazine

IUPAC name

1-({5-[3-(3-fluorophenyl)-124-oxadiazol-5-yl]-2-methylthiophen-3-yl}sulfonyl)-4-(pyridin-2-yl)piperazine

SMILES

Cc(sc(-c1nc(-c2cc(F)ccc2)no1)c1)c1S(N(CC1)CCN1c1ncccc1)(=O)=O

InChI

InChI=1S/C22H20FN5O3S2/c1-15-19(33(29,30)28-11-9-27(10-12-28)20-7-2-3-8-24-20)14-18(32-15)22-25-21(26-31-22)16-5-4-6-17(23)13-16/h2-8,13-14H,9-12H2,1H3

InChI Key

XOCRLGMHJJMNAS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27237447

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

485.56

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

5.085

Distribution Coefficient, logD

5.061

Water Solubility, LogSw

-4.99

Polar Surface Area

76.145

Acid Dissociation Constant (pKa)

24.57

Base Dissociation Constant (pKb)

6.16

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

L233-1703 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L233-1703 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L233-1703?
Check Price and Availability of L233-1703, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L233-1703 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L233-1703
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L233-1703
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L233-1703 available by request