L234-0012 Screening compound: 5-(2,4-dimethyl-1,3-thiazol-5-yl)-3-(4-phenoxyphenyl)-1,2,4-oxadiazole

L234-0012 Screening compound: 5-(2,4-dimethyl-1,3-thiazol-5-yl)-3-(4-phenoxyphenyl)-1,2,4-oxadiazole
L234-0012 Screening compound: 5-(2,4-dimethyl-1,3-thiazol-5-yl)-3-(4-phenoxyphenyl)-1,2,4-oxadiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound L234-0012
5-(2,4-dimethyl-1,3-thiazol-5-yl)-3-(4-phenoxyphenyl)-1,2,4-oxadiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L234-0012

Molecular Formula

C19H15N3O2S (C19 H15 N3 O2 S)

Compound Name

5-(2,4-dimethyl-1,3-thiazol-5-yl)-3-(4-phenoxyphenyl)-1,2,4-oxadiazole

IUPAC name

5-(24-dimethyl-13-thiazol-5-yl)-3-(4-phenoxyphenyl)-124-oxadiazole

SMILES

Cc1c(-c2nc(-c(cc3)ccc3Oc3ccccc3)no2)sc(C)n1

InChI

InChI=1S/C19H15N3O2S/c1-12-17(25-13(2)20-12)19-21-18(22-24-19)14-8-10-16(11-9-14)23-15-6-4-3-5-7-15/h3-11H,1-2H3

InChI Key

NYJJPXYDTZVXMW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27237490

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

349.41

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.552

Distribution Coefficient, logD

5.552

Water Solubility, LogSw

-5.69

Polar Surface Area

48.781

Acid Dissociation Constant (pKa)

30.79

Base Dissociation Constant (pKb)

3.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.50

L234-0012 in Drug Discovery

Included in Screening Libraries

Targeted Diversity Library (40567 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with L234-0012 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L234-0012?
Check Price and Availability of L234-0012, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L234-0012 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L234-0012
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L234-0012
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L234-0012 available by request