L234-0148 Screening compound: 4-{[3-(4-phenoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}-3,4-dihydro-2H-1,4-benzoxazin-3-one

L234-0148 Screening compound: 4-{[3-(4-phenoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}-3,4-dihydro-2H-1,4-benzoxazin-3-one
L234-0148 Screening compound: 4-{[3-(4-phenoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}-3,4-dihydro-2H-1,4-benzoxazin-3-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L234-0148
4-{[3-(4-phenoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}-3,4-dihydro-2H-1,4-benzoxazin-3-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L234-0148

Molecular Formula

C23H17N3O4 (C23 H17 N3 O4)

Compound Name

4-{[3-(4-phenoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}-3,4-dihydro-2H-1,4-benzoxazin-3-one

IUPAC name

4-{[3-(4-phenoxyphenyl)-124-oxadiazol-5-yl]methyl}-34-dihydro-2H-14-benzoxazin-3-one

SMILES

O=C1N(Cc2nc(-c(cc3)ccc3Oc3ccccc3)no2)c(cccc2)c2OC1

InChI

InChI=1S/C23H17N3O4/c27-22-15-28-20-9-5-4-8-19(20)26(22)14-21-24-23(25-30-21)16-10-12-18(13-11-16)29-17-6-2-1-3-7-17/h1-13H,14-15H2

InChI Key

JJBUNIDZALESDO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27237501

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

399.41

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.733

Distribution Coefficient, logD

4.733

Water Solubility, LogSw

-4.89

Polar Surface Area

62.159

Acid Dissociation Constant (pKa)

20.50

Base Dissociation Constant (pKb)

-6.78

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.70

L234-0148 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with L234-0148 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L234-0148?
Check Price and Availability of L234-0148, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L234-0148 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L234-0148
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L234-0148
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L234-0148 available by request