L234-0456 Screening compound: N-(4-{3-[4-(3-methylphenoxy)phenyl]-1,2,4-oxadiazol-5-yl}phenyl)furan-2-carboxamide

L234-0456 Screening compound: N-(4-{3-[4-(3-methylphenoxy)phenyl]-1,2,4-oxadiazol-5-yl}phenyl)furan-2-carboxamide
L234-0456 Screening compound: N-(4-{3-[4-(3-methylphenoxy)phenyl]-1,2,4-oxadiazol-5-yl}phenyl)furan-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L234-0456
N-(4-{3-[4-(3-methylphenoxy)phenyl]-1,2,4-oxadiazol-5-yl}phenyl)furan-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L234-0456

Molecular Formula

C26H19N3O4 (C26 H19 N3 O4)

Compound Name

N-(4-{3-[4-(3-methylphenoxy)phenyl]-1,2,4-oxadiazol-5-yl}phenyl)furan-2-carboxamide

IUPAC name

N-(4-{3-[4-(3-methylphenoxy)phenyl]-124-oxadiazol-5-yl}phenyl)furan-2-carboxamide

SMILES

Cc1cccc(Oc(cc2)ccc2-c2noc(-c(cc3)ccc3NC(c3ccco3)=O)n2)c1

InChI

InChI=1S/C26H19N3O4/c1-17-4-2-5-22(16-17)32-21-13-9-18(10-14-21)24-28-26(33-29-24)19-7-11-20(12-8-19)27-25(30)23-6-3-15-31-23/h2-16H,1H3,(H,27,30)

InChI Key

MNPOGXRHFSJWHB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27237532

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

437.45

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

6.439

Distribution Coefficient, logD

6.439

Water Solubility, LogSw

-5.71

Polar Surface Area

70.062

Acid Dissociation Constant (pKa)

12.09

Base Dissociation Constant (pKb)

-1.40

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

3.80

L234-0456 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Immunological Library (6760 compounds)

Protein-Protein Interaction Library (218420 compounds)

PD-1/L1 Library (498 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Mechanism of action:
  • PPI modulators
Targets:
  • Others

References: we are preparing a list of scientific research reports with L234-0456 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L234-0456?
Check Price and Availability of L234-0456, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L234-0456 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L234-0456
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L234-0456
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L234-0456 available by request