L234-1227 Screening compound: 5-(1-ETHYL-1H-PYRAZOL-3-YL)-3-[4-(4-FLUOROPHENOXY)PHENYL]-1,2,4-OXADIAZOLE

L234-1227 Screening compound: 5-(1-ETHYL-1H-PYRAZOL-3-YL)-3-[4-(4-FLUOROPHENOXY)PHENYL]-1,2,4-OXADIAZOLE
L234-1227 Screening compound: 5-(1-ETHYL-1H-PYRAZOL-3-YL)-3-[4-(4-FLUOROPHENOXY)PHENYL]-1,2,4-OXADIAZOLE alternative view

Chemical Structure Depiction of ChemDiv screening compound L234-1227
5-(1-ETHYL-1H-PYRAZOL-3-YL)-3-[4-(4-FLUOROPHENOXY)PHENYL]-1,2,4-OXADIAZOLE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L234-1227

Molecular Formula

C19H15FN4O2 (C19 H15 FN4 O2)

Compound Name

5-(1-ETHYL-1H-PYRAZOL-3-YL)-3-[4-(4-FLUOROPHENOXY)PHENYL]-1,2,4-OXADIAZOLE

IUPAC name

5-(1-ethyl-1H-pyrazol-3-yl)-3-[4-(4-fluorophenoxy)phenyl]-124-oxadiazole

SMILES

CCn(cc1)nc1-c1nc(-c(cc2)ccc2Oc(cc2)ccc2F)no1

InChI

InChI=1S/C19H15FN4O2/c1-2-24-12-11-17(22-24)19-21-18(23-26-19)13-3-7-15(8-4-13)25-16-9-5-14(20)6-10-16/h3-12H,2H2,1H3

InChI Key

JLCCYYKSQBRPFM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27237638

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

350.35

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.515

Distribution Coefficient, logD

4.515

Water Solubility, LogSw

-4.36

Polar Surface Area

52.777

Acid Dissociation Constant (pKa)

29.70

Base Dissociation Constant (pKb)

-1.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.50

L234-1227 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with L234-1227 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L234-1227?
Check Price and Availability of L234-1227, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L234-1227 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L234-1227
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L234-1227
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L234-1227 available by request