L239-0295 Screening compound: 2-[3-(pyrrolidine-1-carbonyl)-1H-indazol-1-yl]-N-[2-(thiophen-2-yl)ethyl]acetamide

L239-0295 Screening compound: 2-[3-(pyrrolidine-1-carbonyl)-1H-indazol-1-yl]-N-[2-(thiophen-2-yl)ethyl]acetamide
L239-0295 Screening compound: 2-[3-(pyrrolidine-1-carbonyl)-1H-indazol-1-yl]-N-[2-(thiophen-2-yl)ethyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L239-0295
2-[3-(pyrrolidine-1-carbonyl)-1H-indazol-1-yl]-N-[2-(thiophen-2-yl)ethyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L239-0295

Molecular Formula

C20H22N4O2S (C20 H22 N4 O2 S)

Compound Name

2-[3-(pyrrolidine-1-carbonyl)-1H-indazol-1-yl]-N-[2-(thiophen-2-yl)ethyl]acetamide

IUPAC name

2-[3-(pyrrolidine-1-carbonyl)-1H-indazol-1-yl]-N-[2-(thiophen-2-yl)ethyl]acetamide

SMILES

O=C(Cn1nc(C(N2CCCC2)=O)c2c1cccc2)NCCc1cccs1

InChI

InChI=1S/C20H22N4O2S/c25-18(21-10-9-15-6-5-13-27-15)14-24-17-8-2-1-7-16(17)19(22-24)20(26)23-11-3-4-12-23/h1-2,5-8,13H,3-4,9-12,14H2,(H,21,25)

InChI Key

YDFVYRMUOVMRIL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27237696

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

382.49

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.073

Distribution Coefficient, logD

2.073

Water Solubility, LogSw

-2.70

Polar Surface Area

56.563

Acid Dissociation Constant (pKa)

14.62

Base Dissociation Constant (pKb)

2.11

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.00

L239-0295 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

KRAS-Targeted Library (16000 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L239-0295 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L239-0295?
Check Price and Availability of L239-0295, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L239-0295 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L239-0295
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L239-0295
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L239-0295 available by request