L244-0044 Screening compound: 2-[3-(4-phenylpiperazine-1-carbonyl)piperidin-1-yl]-5H,6H,7H,8H,9H-[1,3,4]thiadiazolo[2,3-b]quinazolin-5-one

L244-0044 Screening compound: 2-[3-(4-phenylpiperazine-1-carbonyl)piperidin-1-yl]-5H,6H,7H,8H,9H-[1,3,4]thiadiazolo[2,3-b]quinazolin-5-one
L244-0044 Screening compound: 2-[3-(4-phenylpiperazine-1-carbonyl)piperidin-1-yl]-5H,6H,7H,8H,9H-[1,3,4]thiadiazolo[2,3-b]quinazolin-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L244-0044
2-[3-(4-phenylpiperazine-1-carbonyl)piperidin-1-yl]-5H,6H,7H,8H,9H-[1,3,4]thiadiazolo[2,3-b]quinazolin-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L244-0044

Molecular Formula

C25H30N6O2S (C25 H30 N6 O2 S)

Compound Name

2-[3-(4-phenylpiperazine-1-carbonyl)piperidin-1-yl]-5H,6H,7H,8H,9H-[1,3,4]thiadiazolo[2,3-b]quinazolin-5-one

IUPAC name

2-[3-(4-phenylpiperazine-1-carbonyl)piperidin-1-yl]-5H6H7H8H9H-[134]thiadiazolo[23-b]quinazolin-5-one

SMILES

O=C(C(CCC1)CN1C(SC1=NC2=C3CCCC2)=NN1C3=O)N(CC1)CCN1c1ccccc1

InChI

InChI=1S/C25H30N6O2S/c32-22(29-15-13-28(14-16-29)19-8-2-1-3-9-19)18-7-6-12-30(17-18)25-27-31-23(33)20-10-4-5-11-21(20)26-24(31)34-25/h1-3,8-9,18H,4-7,10-17H2/t18-/m0/s1

InChI Key

IOBHWGZVOYIFBB-SFHVURJKSA-N

MDL Number (MFCD)

MFCD15120771

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

478.62

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.921

Distribution Coefficient, logD

2.921

Water Solubility, LogSw

-3.23

Polar Surface Area

60.650

Acid Dissociation Constant (pKa)

22.98

Base Dissociation Constant (pKb)

-5.68

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

52.00

L244-0044 in Drug Discovery

Included in Screening Libraries

Cysteine Proteases Inhibitors Library (7839 compounds)

GPCR Targeted Library (31838 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • Proteases
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L244-0044 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L244-0044?
Check Price and Availability of L244-0044, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L244-0044 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L244-0044
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L244-0044
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L244-0044 available by request