L244-0108 Screening compound: 2-{3-[4-(2-fluorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-5H,6H,7H,8H,9H-[1,3,4]thiadiazolo[2,3-b]quinazolin-5-one

L244-0108 Screening compound: 2-{3-[4-(2-fluorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-5H,6H,7H,8H,9H-[1,3,4]thiadiazolo[2,3-b]quinazolin-5-one
L244-0108 Screening compound: 2-{3-[4-(2-fluorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-5H,6H,7H,8H,9H-[1,3,4]thiadiazolo[2,3-b]quinazolin-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L244-0108
2-{3-[4-(2-fluorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-5H,6H,7H,8H,9H-[1,3,4]thiadiazolo[2,3-b]quinazolin-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L244-0108

Molecular Formula

C25H29FN6O2S (C25 H29 FN6 O2 S)

Compound Name

2-{3-[4-(2-fluorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-5H,6H,7H,8H,9H-[1,3,4]thiadiazolo[2,3-b]quinazolin-5-one

IUPAC name

2-{3-[4-(2-fluorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-5H6H7H8H9H-[134]thiadiazolo[23-b]quinazolin-5-one

SMILES

O=C(C(CCC1)CN1C(SC1=NC2=C3CCCC2)=NN1C3=O)N(CC1)CCN1c(cccc1)c1F

InChI

InChI=1S/C25H29FN6O2S/c26-19-8-2-4-10-21(19)29-12-14-30(15-13-29)22(33)17-6-5-11-31(16-17)25-28-32-23(34)18-7-1-3-9-20(18)27-24(32)35-25/h2,4,8,10,17H,1,3,5-7,9,11-16H2/t17-/m0/s1

InChI Key

WCXYCTYIFQXCFP-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD15120799

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

496.61

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.100

Distribution Coefficient, logD

3.099

Water Solubility, LogSw

-3.40

Polar Surface Area

60.350

Acid Dissociation Constant (pKa)

22.98

Base Dissociation Constant (pKb)

-5.68

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

52.00

L244-0108 in Drug Discovery

Included in Screening Libraries

Cysteine Proteases Inhibitors Library (7839 compounds)

SmartTM Library (51161 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
Targets:
  • Proteases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with L244-0108 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L244-0108?
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What is the minimum amount of L244-0108 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L244-0108
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L244-0108
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L244-0108 available by request