L244-0148 Screening compound: N-{2-[benzyl(methyl)amino]ethyl}-1-(5-oxo-6,7,8,9-tetrahydro-5H-[1,3,4]thiadiazolo[2,3-b]quinazolin-2-yl)-3-piperidinecarboxamide

L244-0148 Screening compound: N-{2-[benzyl(methyl)amino]ethyl}-1-(5-oxo-6,7,8,9-tetrahydro-5H-[1,3,4]thiadiazolo[2,3-b]quinazolin-2-yl)-3-piperidinecarboxamide
L244-0148 Screening compound: N-{2-[benzyl(methyl)amino]ethyl}-1-(5-oxo-6,7,8,9-tetrahydro-5H-[1,3,4]thiadiazolo[2,3-b]quinazolin-2-yl)-3-piperidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L244-0148
N-{2-[benzyl(methyl)amino]ethyl}-1-(5-oxo-6,7,8,9-tetrahydro-5H-[1,3,4]thiadiazolo[2,3-b]quinazolin-2-yl)-3-piperidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L244-0148

Molecular Formula

C25H32N6O2S (C25 H32 N6 O2 S)

Compound Name

N-{2-[benzyl(methyl)amino]ethyl}-1-(5-oxo-6,7,8,9-tetrahydro-5H-[1,3,4]thiadiazolo[2,3-b]quinazolin-2-yl)-3-piperidinecarboxamide

IUPAC name

N-{2-[benzyl(methyl)amino]ethyl}-1-{5-oxo-5H6H7H8H9H-[134]thiadiazolo[23-b]quinazolin-2-yl}piperidine-3-carboxamide

SMILES

CN(CCNC(C(CCC1)CN1C(SC1=NC2=C3CCCC2)=NN1C3=O)=O)Cc1ccccc1

InChI

InChI=1S/C25H32N6O2S/c1-29(16-18-8-3-2-4-9-18)15-13-26-22(32)19-10-7-14-30(17-19)25-28-31-23(33)20-11-5-6-12-21(20)27-24(31)34-25/h2-4,8-9,19H,5-7,10-17H2,1H3,(H,26,32)/t19-/m0/s1

InChI Key

CRODOKUWHKTJBP-IBGZPJMESA-N

MDL Number (MFCD)

MFCD15120812

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

480.63

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.372

Distribution Coefficient, logD

1.649

Water Solubility, LogSw

-2.76

Polar Surface Area

69.091

Acid Dissociation Constant (pKa)

13.28

Base Dissociation Constant (pKb)

8.03

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

52.00

L244-0148 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Cysteine Proteases Inhibitors Library (7839 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with L244-0148 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L244-0148?
Check Price and Availability of L244-0148, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L244-0148 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L244-0148
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L244-0148
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L244-0148 available by request