L249-1366 Screening compound: 2-[1-(2-cyclopropyl-1,3-benzoxazole-5-carbonyl)piperidin-4-yl]-N-[(3-fluorophenyl)methyl]acetamide

L249-1366 Screening compound: 2-[1-(2-cyclopropyl-1,3-benzoxazole-5-carbonyl)piperidin-4-yl]-N-[(3-fluorophenyl)methyl]acetamide
L249-1366 Screening compound: 2-[1-(2-cyclopropyl-1,3-benzoxazole-5-carbonyl)piperidin-4-yl]-N-[(3-fluorophenyl)methyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L249-1366
2-[1-(2-cyclopropyl-1,3-benzoxazole-5-carbonyl)piperidin-4-yl]-N-[(3-fluorophenyl)methyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L249-1366

Molecular Formula

C25H26FN3O3 (C25 H26 FN3 O3)

Compound Name

2-[1-(2-cyclopropyl-1,3-benzoxazole-5-carbonyl)piperidin-4-yl]-N-[(3-fluorophenyl)methyl]acetamide

IUPAC name

2-[1-(2-cyclopropyl-13-benzoxazole-5-carbonyl)piperidin-4-yl]-N-[(3-fluorophenyl)methyl]acetamide

SMILES

O=C(CC(CC1)CCN1C(c(cc1)cc2c1oc(C1CC1)n2)=O)NCc1cccc(F)c1

InChI

InChI=1S/C25H26FN3O3/c26-20-3-1-2-17(12-20)15-27-23(30)13-16-8-10-29(11-9-16)25(31)19-6-7-22-21(14-19)28-24(32-22)18-4-5-18/h1-3,6-7,12,14,16,18H,4-5,8-11,13,15H2,(H,27,30)

InChI Key

TULSENUVBUISCX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27237904

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

435.5

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.818

Distribution Coefficient, logD

3.818

Water Solubility, LogSw

-4.19

Polar Surface Area

58.420

Acid Dissociation Constant (pKa)

12.82

Base Dissociation Constant (pKb)

0.48

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

L249-1366 in Drug Discovery

Included in Screening Libraries

MCL1 Targeted Library (12200 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
Targets:
  • Proteases
  • Phosphatases

References: we are preparing a list of scientific research reports with L249-1366 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L249-1366?
Check Price and Availability of L249-1366, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L249-1366 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L249-1366
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L249-1366
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L249-1366 available by request