L249-1700 Screening compound: 2-{1-[2-(4-methylphenyl)-1,3-benzoxazole-5-carbonyl]piperidin-4-yl}-N-[2-(piperidin-1-yl)ethyl]acetamide

L249-1700 Screening compound: 2-{1-[2-(4-methylphenyl)-1,3-benzoxazole-5-carbonyl]piperidin-4-yl}-N-[2-(piperidin-1-yl)ethyl]acetamide
L249-1700 Screening compound: 2-{1-[2-(4-methylphenyl)-1,3-benzoxazole-5-carbonyl]piperidin-4-yl}-N-[2-(piperidin-1-yl)ethyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L249-1700
2-{1-[2-(4-methylphenyl)-1,3-benzoxazole-5-carbonyl]piperidin-4-yl}-N-[2-(piperidin-1-yl)ethyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L249-1700

Molecular Formula

C29H36N4O3 (C29 H36 N4 O3)

Compound Name

2-{1-[2-(4-methylphenyl)-1,3-benzoxazole-5-carbonyl]piperidin-4-yl}-N-[2-(piperidin-1-yl)ethyl]acetamide

IUPAC name

2-{1-[2-(4-methylphenyl)-13-benzoxazole-5-carbonyl]piperidin-4-yl}-N-[2-(piperidin-1-yl)ethyl]acetamide

SMILES

Cc(cc1)ccc1-c1nc(cc(cc2)C(N3CCC(CC(NCCN4CCCCC4)=O)CC3)=O)c2o1

InChI

InChI=1S/C29H36N4O3/c1-21-5-7-23(8-6-21)28-31-25-20-24(9-10-26(25)36-28)29(35)33-16-11-22(12-17-33)19-27(34)30-13-18-32-14-3-2-4-15-32/h5-10,20,22H,2-4,11-19H2,1H3,(H,30,34)

InChI Key

DLVRCOUNRJTQMB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27237972

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

488.63

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.624

Distribution Coefficient, logD

1.900

Water Solubility, LogSw

-3.72

Polar Surface Area

61.721

Acid Dissociation Constant (pKa)

13.60

Base Dissociation Constant (pKb)

9.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

48.30

L249-1700 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

MCL1 Targeted Library (12200 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with L249-1700 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L249-1700?
Check Price and Availability of L249-1700, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L249-1700 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L249-1700
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L249-1700
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L249-1700 available by request