L251-0005 Screening compound: 2-{1-[4-methyl-2-(4-methylphenyl)-1,3-thiazole-5-carbonyl]piperidin-4-yl}-N-[(pyridin-3-yl)methyl]acetamide

L251-0005 Screening compound: 2-{1-[4-methyl-2-(4-methylphenyl)-1,3-thiazole-5-carbonyl]piperidin-4-yl}-N-[(pyridin-3-yl)methyl]acetamide
L251-0005 Screening compound: 2-{1-[4-methyl-2-(4-methylphenyl)-1,3-thiazole-5-carbonyl]piperidin-4-yl}-N-[(pyridin-3-yl)methyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L251-0005
2-{1-[4-methyl-2-(4-methylphenyl)-1,3-thiazole-5-carbonyl]piperidin-4-yl}-N-[(pyridin-3-yl)methyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L251-0005

Molecular Formula

C25H28N4O2S (C25 H28 N4 O2 S)

Compound Name

2-{1-[4-methyl-2-(4-methylphenyl)-1,3-thiazole-5-carbonyl]piperidin-4-yl}-N-[(pyridin-3-yl)methyl]acetamide

IUPAC name

2-{1-[4-methyl-2-(4-methylphenyl)-13-thiazole-5-carbonyl]piperidin-4-yl}-N-[(pyridin-3-yl)methyl]acetamide

SMILES

Cc1c(C(N2CCC(CC(NCc3cnccc3)=O)CC2)=O)sc(-c2ccc(C)cc2)n1

InChI

InChI=1S/C25H28N4O2S/c1-17-5-7-21(8-6-17)24-28-18(2)23(32-24)25(31)29-12-9-19(10-13-29)14-22(30)27-16-20-4-3-11-26-15-20/h3-8,11,15,19H,9-10,12-14,16H2,1-2H3,(H,27,30)

InChI Key

VOUIYYIPEKYZEQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27237995

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

448.59

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.687

Distribution Coefficient, logD

3.684

Water Solubility, LogSw

-3.69

Polar Surface Area

60.915

Acid Dissociation Constant (pKa)

13.61

Base Dissociation Constant (pKb)

5.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.00

L251-0005 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

GPCR Targeted Library (31838 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L251-0005 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L251-0005?
Check Price and Availability of L251-0005, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L251-0005 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L251-0005
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L251-0005
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L251-0005 available by request