L251-0034 Screening compound: 1-(azepan-1-yl)-2-{1-[4-methyl-2-(4-methylphenyl)-1,3-thiazole-5-carbonyl]piperidin-4-yl}ethan-1-one

L251-0034 Screening compound: 1-(azepan-1-yl)-2-{1-[4-methyl-2-(4-methylphenyl)-1,3-thiazole-5-carbonyl]piperidin-4-yl}ethan-1-one
L251-0034 Screening compound: 1-(azepan-1-yl)-2-{1-[4-methyl-2-(4-methylphenyl)-1,3-thiazole-5-carbonyl]piperidin-4-yl}ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L251-0034
1-(azepan-1-yl)-2-{1-[4-methyl-2-(4-methylphenyl)-1,3-thiazole-5-carbonyl]piperidin-4-yl}ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L251-0034

Molecular Formula

C25H33N3O2S (C25 H33 N3 O2 S)

Compound Name

1-(azepan-1-yl)-2-{1-[4-methyl-2-(4-methylphenyl)-1,3-thiazole-5-carbonyl]piperidin-4-yl}ethan-1-one

IUPAC name

1-(azepan-1-yl)-2-{1-[4-methyl-2-(4-methylphenyl)-13-thiazole-5-carbonyl]piperidin-4-yl}ethan-1-one

SMILES

Cc1c(C(N2CCC(CC(N3CCCCCC3)=O)CC2)=O)sc(-c2ccc(C)cc2)n1

InChI

InChI=1S/C25H33N3O2S/c1-18-7-9-21(10-8-18)24-26-19(2)23(31-24)25(30)28-15-11-20(12-16-28)17-22(29)27-13-5-3-4-6-14-27/h7-10,20H,3-6,11-17H2,1-2H3

InChI Key

PWAJFTOPFTVSGI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27238003

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

439.62

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.055

Distribution Coefficient, logD

5.055

Water Solubility, LogSw

-4.57

Polar Surface Area

43.649

Acid Dissociation Constant (pKa)

24.23

Base Dissociation Constant (pKb)

2.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

56.00

L251-0034 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L251-0034 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L251-0034?
Check Price and Availability of L251-0034, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L251-0034 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L251-0034
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L251-0034
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L251-0034 available by request