L251-0116 Screening compound: 2-{1-[4-methyl-2-(4-methylphenyl)-1,3-thiazole-5-carbonyl]piperidin-4-yl}-N-[3-(pyrrolidin-1-yl)propyl]acetamide

L251-0116 Screening compound: 2-{1-[4-methyl-2-(4-methylphenyl)-1,3-thiazole-5-carbonyl]piperidin-4-yl}-N-[3-(pyrrolidin-1-yl)propyl]acetamide
L251-0116 Screening compound: 2-{1-[4-methyl-2-(4-methylphenyl)-1,3-thiazole-5-carbonyl]piperidin-4-yl}-N-[3-(pyrrolidin-1-yl)propyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L251-0116
2-{1-[4-methyl-2-(4-methylphenyl)-1,3-thiazole-5-carbonyl]piperidin-4-yl}-N-[3-(pyrrolidin-1-yl)propyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L251-0116

Molecular Formula

C26H36N4O2S (C26 H36 N4 O2 S)

Compound Name

2-{1-[4-methyl-2-(4-methylphenyl)-1,3-thiazole-5-carbonyl]piperidin-4-yl}-N-[3-(pyrrolidin-1-yl)propyl]acetamide

IUPAC name

2-{1-[4-methyl-2-(4-methylphenyl)-13-thiazole-5-carbonyl]piperidin-4-yl}-N-[3-(pyrrolidin-1-yl)propyl]acetamide

SMILES

Cc1c(C(N2CCC(CC(NCCCN3CCCC3)=O)CC2)=O)sc(-c2ccc(C)cc2)n1

InChI

InChI=1S/C26H36N4O2S/c1-19-6-8-22(9-7-19)25-28-20(2)24(33-25)26(32)30-16-10-21(11-17-30)18-23(31)27-12-5-15-29-13-3-4-14-29/h6-9,21H,3-5,10-18H2,1-2H3,(H,27,31)

InChI Key

QYSQIFXUACVUDA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27238031

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

468.66

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.694

Distribution Coefficient, logD

0.603

Water Solubility, LogSw

-3.85

Polar Surface Area

55.587

Acid Dissociation Constant (pKa)

15.33

Base Dissociation Constant (pKb)

10.49

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

57.70

L251-0116 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L251-0116 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L251-0116?
Check Price and Availability of L251-0116, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L251-0116 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L251-0116
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L251-0116
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L251-0116 available by request