L251-1022 Screening compound: N-cycloheptyl-2-{1-[2-(4-fluorophenyl)-4-methyl-1,3-thiazole-5-carbonyl]piperidin-4-yl}acetamide

L251-1022 Screening compound: N-cycloheptyl-2-{1-[2-(4-fluorophenyl)-4-methyl-1,3-thiazole-5-carbonyl]piperidin-4-yl}acetamide
L251-1022 Screening compound: N-cycloheptyl-2-{1-[2-(4-fluorophenyl)-4-methyl-1,3-thiazole-5-carbonyl]piperidin-4-yl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L251-1022
N-cycloheptyl-2-{1-[2-(4-fluorophenyl)-4-methyl-1,3-thiazole-5-carbonyl]piperidin-4-yl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L251-1022

Molecular Formula

C25H32FN3O2S (C25 H32 FN3 O2 S)

Compound Name

N-cycloheptyl-2-{1-[2-(4-fluorophenyl)-4-methyl-1,3-thiazole-5-carbonyl]piperidin-4-yl}acetamide

IUPAC name

N-cycloheptyl-2-{1-[2-(4-fluorophenyl)-4-methyl-13-thiazole-5-carbonyl]piperidin-4-yl}acetamide

SMILES

Cc1c(C(N2CCC(CC(NC3CCCCCC3)=O)CC2)=O)sc(-c(cc2)ccc2F)n1

InChI

InChI=1S/C25H32FN3O2S/c1-17-23(32-24(27-17)19-8-10-20(26)11-9-19)25(31)29-14-12-18(13-15-29)16-22(30)28-21-6-4-2-3-5-7-21/h8-11,18,21H,2-7,12-16H2,1H3,(H,28,30)

InChI Key

UZCBPRGZBBCPBR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27238148

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

457.61

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.524

Distribution Coefficient, logD

5.524

Water Solubility, LogSw

-5.27

Polar Surface Area

51.454

Acid Dissociation Constant (pKa)

14.63

Base Dissociation Constant (pKb)

1.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

56.00

L251-1022 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Soluble Diversity Library (15920 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Mimetics
Mechanism of action:
  • PPI modulators
  • PPI modulators
Therapeutical areas:
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with L251-1022 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L251-1022?
Check Price and Availability of L251-1022, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L251-1022 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L251-1022
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L251-1022
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L251-1022 available by request