L251-1120 Screening compound: 2-{1-[2-(4-fluorophenyl)-4-methyl-1,3-thiazole-5-carbonyl]piperidin-4-yl}-N-[(furan-2-yl)methyl]-N-methylacetamide

L251-1120 Screening compound: 2-{1-[2-(4-fluorophenyl)-4-methyl-1,3-thiazole-5-carbonyl]piperidin-4-yl}-N-[(furan-2-yl)methyl]-N-methylacetamide
L251-1120 Screening compound: 2-{1-[2-(4-fluorophenyl)-4-methyl-1,3-thiazole-5-carbonyl]piperidin-4-yl}-N-[(furan-2-yl)methyl]-N-methylacetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L251-1120
2-{1-[2-(4-fluorophenyl)-4-methyl-1,3-thiazole-5-carbonyl]piperidin-4-yl}-N-[(furan-2-yl)methyl]-N-methylacetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L251-1120

Molecular Formula

C24H26FN3O3S (C24 H26 FN3 O3 S)

Compound Name

2-{1-[2-(4-fluorophenyl)-4-methyl-1,3-thiazole-5-carbonyl]piperidin-4-yl}-N-[(furan-2-yl)methyl]-N-methylacetamide

IUPAC name

2-{1-[2-(4-fluorophenyl)-4-methyl-13-thiazole-5-carbonyl]piperidin-4-yl}-N-[(furan-2-yl)methyl]-N-methylacetamide

SMILES

Cc1c(C(N2CCC(CC(N(C)Cc3ccco3)=O)CC2)=O)sc(-c(cc2)ccc2F)n1

InChI

InChI=1S/C24H26FN3O3S/c1-16-22(32-23(26-16)18-5-7-19(25)8-6-18)24(30)28-11-9-17(10-12-28)14-21(29)27(2)15-20-4-3-13-31-20/h3-8,13,17H,9-12,14-15H2,1-2H3

InChI Key

ISKSCLPIMXPGQF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27238181

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

455.55

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.442

Distribution Coefficient, logD

4.442

Water Solubility, LogSw

-4.28

Polar Surface Area

50.569

Acid Dissociation Constant (pKa)

23.07

Base Dissociation Constant (pKb)

0.82

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

L251-1120 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L251-1120 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L251-1120?
Check Price and Availability of L251-1120, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L251-1120 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L251-1120
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L251-1120
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L251-1120 available by request