L251-1167 Screening compound: 2-{1-[2-(4-fluorophenyl)-4-methyl-1,3-thiazole-5-carbonyl]piperidin-4-yl}-N-propylpropanamide

L251-1167 Screening compound: 2-{1-[2-(4-fluorophenyl)-4-methyl-1,3-thiazole-5-carbonyl]piperidin-4-yl}-N-propylpropanamide
L251-1167 Screening compound: 2-{1-[2-(4-fluorophenyl)-4-methyl-1,3-thiazole-5-carbonyl]piperidin-4-yl}-N-propylpropanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L251-1167
2-{1-[2-(4-fluorophenyl)-4-methyl-1,3-thiazole-5-carbonyl]piperidin-4-yl}-N-propylpropanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L251-1167

Molecular Formula

C22H28FN3O2S (C22 H28 FN3 O2 S)

Compound Name

2-{1-[2-(4-fluorophenyl)-4-methyl-1,3-thiazole-5-carbonyl]piperidin-4-yl}-N-propylpropanamide

IUPAC name

2-{1-[2-(4-fluorophenyl)-4-methyl-13-thiazole-5-carbonyl]piperidin-4-yl}-N-propylpropanamide

SMILES

CCCNC(C(C)C(CC1)CCN1C(c1c(C)nc(-c(cc2)ccc2F)s1)=O)=O

InChI

InChI=1S/C22H28FN3O2S/c1-4-11-24-20(27)14(2)16-9-12-26(13-10-16)22(28)19-15(3)25-21(29-19)17-5-7-18(23)8-6-17/h5-8,14,16H,4,9-13H2,1-3H3,(H,24,27)/t14-/m0/s1

InChI Key

PCTTYYVYSHTYCO-AWEZNQCLSA-N

MDL Number (MFCD)

MFCD27238197

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

417.55

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.882

Distribution Coefficient, logD

3.882

Water Solubility, LogSw

-3.86

Polar Surface Area

51.724

Acid Dissociation Constant (pKa)

15.07

Base Dissociation Constant (pKb)

4.29

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

50.00

L251-1167 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L251-1167 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L251-1167?
Check Price and Availability of L251-1167, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L251-1167 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L251-1167
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L251-1167
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L251-1167 available by request