L256-0197 Screening compound: 2-(4-methoxyphenyl)-N-{2-[1-(4-methylbenzoyl)piperidin-4-yl]ethyl}acetamide

L256-0197 Screening compound: 2-(4-methoxyphenyl)-N-{2-[1-(4-methylbenzoyl)piperidin-4-yl]ethyl}acetamide
L256-0197 Screening compound: 2-(4-methoxyphenyl)-N-{2-[1-(4-methylbenzoyl)piperidin-4-yl]ethyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L256-0197
2-(4-methoxyphenyl)-N-{2-[1-(4-methylbenzoyl)piperidin-4-yl]ethyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L256-0197

Molecular Formula

C24H30N2O3 (C24 H30 N2 O3)

Compound Name

2-(4-methoxyphenyl)-N-{2-[1-(4-methylbenzoyl)piperidin-4-yl]ethyl}acetamide

IUPAC name

2-(4-methoxyphenyl)-N-{2-[1-(4-methylbenzoyl)piperidin-4-yl]ethyl}acetamide

SMILES

Cc(cc1)ccc1C(N1CCC(CCNC(Cc(cc2)ccc2OC)=O)CC1)=O

InChI

InChI=1S/C24H30N2O3/c1-18-3-7-21(8-4-18)24(28)26-15-12-19(13-16-26)11-14-25-23(27)17-20-5-9-22(29-2)10-6-20/h3-10,19H,11-17H2,1-2H3,(H,25,27)

InChI Key

ZEDRUGIPZJOORL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15121059

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

394.51

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.088

Distribution Coefficient, logD

3.088

Water Solubility, LogSw

-3.23

Polar Surface Area

48.472

Acid Dissociation Constant (pKa)

13.77

Base Dissociation Constant (pKb)

3.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.70

L256-0197 in Drug Discovery

Included in Screening Libraries

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds
Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with L256-0197 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L256-0197?
Check Price and Availability of L256-0197, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L256-0197 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L256-0197
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L256-0197
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L256-0197 available by request