L257-0124 Screening compound: N-{2-[1-(4-fluorobenzoyl)piperidin-4-yl]ethyl}-5,6,7,8-tetrahydronaphthalene-2-sulfonamide

L257-0124 Screening compound: N-{2-[1-(4-fluorobenzoyl)piperidin-4-yl]ethyl}-5,6,7,8-tetrahydronaphthalene-2-sulfonamide
L257-0124 Screening compound: N-{2-[1-(4-fluorobenzoyl)piperidin-4-yl]ethyl}-5,6,7,8-tetrahydronaphthalene-2-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L257-0124
N-{2-[1-(4-fluorobenzoyl)piperidin-4-yl]ethyl}-5,6,7,8-tetrahydronaphthalene-2-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L257-0124

Molecular Formula

C24H29FN2O3S (C24 H29 FN2 O3 S)

Compound Name

N-{2-[1-(4-fluorobenzoyl)piperidin-4-yl]ethyl}-5,6,7,8-tetrahydronaphthalene-2-sulfonamide

IUPAC name

N-{2-[1-(4-fluorobenzoyl)piperidin-4-yl]ethyl}-5678-tetrahydronaphthalene-2-sulfonamide

SMILES

O=C(c(cc1)ccc1F)N1CCC(CCNS(c2cc(CCCC3)c3cc2)(=O)=O)CC1

InChI

InChI=1S/C24H29FN2O3S/c25-22-8-5-20(6-9-22)24(28)27-15-12-18(13-16-27)11-14-26-31(29,30)23-10-7-19-3-1-2-4-21(19)17-23/h5-10,17-18,26H,1-4,11-16H2

InChI Key

KBGFQCDISMIXLI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27238250

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

444.57

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.610

Distribution Coefficient, logD

4.610

Water Solubility, LogSw

-4.50

Polar Surface Area

58.407

Acid Dissociation Constant (pKa)

11.63

Base Dissociation Constant (pKb)

-2.34

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.80

L257-0124 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L257-0124 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L257-0124?
Check Price and Availability of L257-0124, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L257-0124 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L257-0124
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L257-0124
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L257-0124 available by request