L257-0287 Screening compound: N~1~-[2-(1-benzoyl-4-piperidyl)ethyl]-3,4-dimethoxy-1-benzenesulfonamide

L257-0287 Screening compound: N~1~-[2-(1-benzoyl-4-piperidyl)ethyl]-3,4-dimethoxy-1-benzenesulfonamide
L257-0287 Screening compound: N~1~-[2-(1-benzoyl-4-piperidyl)ethyl]-3,4-dimethoxy-1-benzenesulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L257-0287
N~1~-[2-(1-benzoyl-4-piperidyl)ethyl]-3,4-dimethoxy-1-benzenesulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L257-0287

Molecular Formula

C22H28N2O5S (C22 H28 N2 O5 S)

Compound Name

N~1~-[2-(1-benzoyl-4-piperidyl)ethyl]-3,4-dimethoxy-1-benzenesulfonamide

IUPAC name

N-[2-(1-benzoylpiperidin-4-yl)ethyl]-34-dimethoxybenzene-1-sulfonamide

SMILES

COc(ccc(S(NCCC(CC1)CCN1C(c1ccccc1)=O)(=O)=O)c1)c1OC

InChI

InChI=1S/C22H28N2O5S/c1-28-20-9-8-19(16-21(20)29-2)30(26,27)23-13-10-17-11-14-24(15-12-17)22(25)18-6-4-3-5-7-18/h3-9,16-17,23H,10-15H2,1-2H3

InChI Key

KQLOUCIXTHYFNV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27238346

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

432.54

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.741

Distribution Coefficient, logD

2.741

Water Solubility, LogSw

-3.58

Polar Surface Area

73.747

Acid Dissociation Constant (pKa)

12.06

Base Dissociation Constant (pKb)

-1.94

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.91

L257-0287 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • Receptor's ligands
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L257-0287 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L257-0287?
Check Price and Availability of L257-0287, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L257-0287 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L257-0287
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L257-0287
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L257-0287 available by request