L258-0206 Screening compound: 3-{2-[1-(benzenesulfonyl)piperidin-4-yl]ethyl}-1-(3,4-dimethoxyphenyl)urea

L258-0206 Screening compound: 3-{2-[1-(benzenesulfonyl)piperidin-4-yl]ethyl}-1-(3,4-dimethoxyphenyl)urea
L258-0206 Screening compound: 3-{2-[1-(benzenesulfonyl)piperidin-4-yl]ethyl}-1-(3,4-dimethoxyphenyl)urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L258-0206
3-{2-[1-(benzenesulfonyl)piperidin-4-yl]ethyl}-1-(3,4-dimethoxyphenyl)urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L258-0206

Molecular Formula

C22H29N3O5S (C22 H29 N3 O5 S)

Compound Name

3-{2-[1-(benzenesulfonyl)piperidin-4-yl]ethyl}-1-(3,4-dimethoxyphenyl)urea

IUPAC name

3-{2-[1-(benzenesulfonyl)piperidin-4-yl]ethyl}-1-(34-dimethoxyphenyl)urea

SMILES

COc(ccc(NC(NCCC(CC1)CCN1S(c1ccccc1)(=O)=O)=O)c1)c1OC

InChI

InChI=1S/C22H29N3O5S/c1-29-20-9-8-18(16-21(20)30-2)24-22(26)23-13-10-17-11-14-25(15-12-17)31(27,28)19-6-4-3-5-7-19/h3-9,16-17H,10-15H2,1-2H3,(H2,23,24,26)

InChI Key

JKLAOQQPFPWKFK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27238451

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

447.56

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.077

Distribution Coefficient, logD

3.077

Water Solubility, LogSw

-3.62

Polar Surface Area

80.677

Acid Dissociation Constant (pKa)

12.51

Base Dissociation Constant (pKb)

2.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.90

L258-0206 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Antiviral Library (67538 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds
  • Mimetics

References: we are preparing a list of scientific research reports with L258-0206 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L258-0206?
Check Price and Availability of L258-0206, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L258-0206 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L258-0206
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L258-0206
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L258-0206 available by request