L259-0295 Screening compound: 2-{2-[(4-fluorophenyl)sulfanyl]-1H-indol-3-yl}-1-(morpholin-4-yl)ethan-1-one

L259-0295 Screening compound: 2-{2-[(4-fluorophenyl)sulfanyl]-1H-indol-3-yl}-1-(morpholin-4-yl)ethan-1-one
L259-0295 Screening compound: 2-{2-[(4-fluorophenyl)sulfanyl]-1H-indol-3-yl}-1-(morpholin-4-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L259-0295
2-{2-[(4-fluorophenyl)sulfanyl]-1H-indol-3-yl}-1-(morpholin-4-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L259-0295

Molecular Formula

C20H19FN2O2S (C20 H19 FN2 O2 S)

Compound Name

2-{2-[(4-fluorophenyl)sulfanyl]-1H-indol-3-yl}-1-(morpholin-4-yl)ethan-1-one

IUPAC name

2-{2-[(4-fluorophenyl)sulfanyl]-1H-indol-3-yl}-1-(morpholin-4-yl)ethan-1-one

SMILES

O=C(Cc(c(cccc1)c1[nH]1)c1Sc(cc1)ccc1F)N1CCOCC1

InChI

InChI=1S/C20H19FN2O2S/c21-14-5-7-15(8-6-14)26-20-17(16-3-1-2-4-18(16)22-20)13-19(24)23-9-11-25-12-10-23/h1-8,22H,9-13H2

InChI Key

IVDZOSHQSYLIAA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15121149

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

370.45

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.524

Distribution Coefficient, logD

3.524

Water Solubility, LogSw

-3.85

Polar Surface Area

33.477

Acid Dissociation Constant (pKa)

16.33

Base Dissociation Constant (pKb)

-1.00

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

L259-0295 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Indole Derivatives (10091 compounds)

PI3K-Targeted Library (17255 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Structure:
  • Cyclic compounds
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with L259-0295 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L259-0295?
Check Price and Availability of L259-0295, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L259-0295 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L259-0295
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L259-0295
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L259-0295 available by request